Results 111 to 120 of about 214,460 (278)

Bridging the Gap between Theory and Practice in Integrated Care: The Case of the Diabetic Foot Pathway in Tuscany

, 2016
Introduction and Background: As diabetic foot (DF) care benefits from integration, monitoring geographic variations in lower limb Major Amputation rate enables to highlight potential lack of Integrated Care.
Lucia Ricci, NUTI, Sabina, Sabina Nuti, Alberto Piaggesi, Piaggesi, Alberto, GRILLO RUGGIERI, Tommaso, Tommaso Grillo Ruggieri, Bini, Barbara, Ricci, Lucia, Barbara Bini   +9 more
core   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Pathway of patient care on antipsychotics and barriers to better integrated care.

Pathway of patient care on antipsychotics and barriers to better integrated care.
Pyers Symon (18086668), Alan A. Woodall (18086656), Dan W. Joyce (18086665), Lauren E. Walker (7070399), Iain Buchan (379469), Sally B. Sheard (18086662), Aseel S. Abuzour (14053917), Paul Atkinson (4023431), Samantha A. Wilson (18086659), Frances S. Mair (7784447)   +9 more
core   +1 more source

CARIBOU-1: A pilot controlled trial of an Integrated Care Pathway for the treatment of depression in adolescents. [PDF]

JCPP Adv, 2022
Courtney DB, Cheung A, Henderson J, Bennett K, Wang W, Chen S, Battaglia M, Strauss J, Mitchell R, Wang K, Relihan J, Prebeg M, Darnay K, Szatmari P.   +13 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Development of a Person-Centred Coordinated Care Pathway in Swedish Healthcare for Low Back Pain

Introduction: This project aimed to develop a Person-Centred Co-ordinated Care (P3C) pathway for low back pain (LBP). Description: A national working group was formed consisting of representatives from all regional healthcare organisations in Sweden and ...
Niper, Åsa,, Christian Simonsberg, Lindström, Ann-Charlotte,, Abbott, Allan, Engström, Mimmi,, Ekman, Per, Linton, Steven J., Torstensson, Thomas,, Allan Abbott, Lindström, Ann-Charlotte, Simonsberg, Christian, Petersson, Annelie,, Annelie Petersson, Mimmi Engström, Torstensson, Thomas, Malin Forsbrand, Linton, Steven J.,, Simonsberg, Christian,, Olsson, Tommy,, Thomas Torstensson, Ullmark, Gösta,, Peter Försth, Greim, Gudrun,, Ekman, Per,, Marc Karlsson, Engström, Mimmi, Olsson, Tommy, Försth, Peter,, Ann-Charlotte Lindström, Forsbrand, Malin,, Per Ekman, Forsbrand, Malin, Niper, Åsa, Försth, Peter, Steven J. Linton, Åsa Niper, Klaff, Sammy, Greim, Gudrun, Ullmark, Gösta, Karlsson, Marc, Sammy Klaff, Tommy Olsson, Abbott, Allan,, Gudrun Greim, Gösta Ullmark, Klaff, Sammy,, Petersson, Annelie, Karlsson, Marc,   +47 more
core   +1 more source

An Integrated Care Pathway for the Last Two Days of Life: A Pathway for Implementing a Pathway

, 2003
Aim of the Paper: To offer colleagues a method of monitoring the process of implementing an integrated care pathway (ICP) on a local level or, across a wide area.
Ilora Finlay, Andrew Fowell, Lindsey Minto, Ros Johnstone   +3 more
core   +1 more source

Developing an integrated depression and tuberculosis care pathway using a co-design approach in a low-resource setting

International Journal of Mental Health Systems
Background Evidence suggests the use of a participatory approach for the improvement of TB care, however, there is limited evidence on how integrated depression screening and care could be delivered with TB services.
Olamide Todowede, Zara Nisar, Saima Afaq, Sushama Kanan, Aliya Ayub, Rumana Huque, Akhtar Hussain, Mudasser Shehzad, Najma Siddiqi   +8 more
doaj   +1 more source

A Novel Approach to Delivering Evidence-based, High-quality Care in Psychiatry Through an Electronic Integrated Care Pathway (eICP) Pilot. [PDF]

Psychiatr Q, 2023
Li L, Kruger M, Kim N, Ong S, Riley S, Cameron K, Koslosky K, Rhodes D.   +7 more
europepmc   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source