Results 51 to 60 of about 157,997 (307)

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Piezoelectric MEMS microphones based on rib structures and single crystal PZT thin film

Microsystems & Nanoengineering
In this study, a controllable mass‒frequency tuning method is presented using the etching of rib structures on a single-crystal PZT membrane. The rib structures were optimized to reduce the membrane mass while maintaining the stiffness; therefore, the ...
Zhiwei You, Jinghan Gan, Chong Yang, Renati Tuerhong, Lei Zhao, Yipeng Lu   +5 more
doaj   +1 more source

Landauer‐QFLPS Model for Mixed Schottky‐Ohmic Contact Two‐Dimensional Transistors

Advanced Science, 2023
Two‐dimensional material‐based field‐effect transistors (2DM‐FETs) are playing a revolutionary role in electronic devices. However, before electronic design automation (EDA) for 2DM‐FETs can be achieved, it remains necessary to determine how to ...
Zhao‐Yi Yan, Zhan Hou, Kan‐Hao Xue, He Tian, Tian Lu, Junying Xue, Fan Wu, Ruiting Zhao, Minghao Shao, Jianlan Yan, Anzhi Yan, Zhenze Wang, Penghui Shen, Mingyue Zhao, Xiangshui Miao, Zhaoyang Lin, Houfang Liu, Yi Yang, Tian‐Ling Ren   +18 more
doaj   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Electrothermal co-optimization of 2.5D power distribution network with TTSV cooling

Scientific Reports
Thermal and power integrity management remains a fundamental challenge in 2.5-dimensional (2.5D) integrated microsystem design. This paper proposes an electrothermal co-optimization design methodology for a 2.5D power distribution network with thermal ...
Yang Wang, Changle Zhi, Gang Dong, Daihang Liu, Deguang Yang, Zhangming Zhu   +5 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Energy‐Efficient Online Training with In Situ Parallel Computing on Electrochemical Memory Arrays

Advanced Intelligent Systems
The rapid development of deep learning enables significant breakthroughs for intelligent edge‐terminal devices. However, neural network training for edge computing is currently overly dependent on cloud service platforms, resulting in low adaptivity for ...
Yingming Lu, Zhen Yang, Yaoyu Tao, Lei Cai, Teng Zhang, Longhao Yan, Ru Huang, Yuchao Yang   +7 more
doaj   +1 more source

Clinical Spectrum and Outcomes of SOX1 Antibody‐Associated Paraneoplastic Neurological Syndromes: A Chinese Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye, Zu‐Ying Kuang, Bo Li, Meng‐Qiu Pan, Li‐Hua Zhou, Yang‐Yang Dai, Si‐Fen Xie, Xian‐Guang Lin, Ye‐Peng Hu, Li‐Hong Jiang, Zhan‐Hang Wang, Wei‐Jing Zhang   +11 more
wiley   +1 more source

Ultra-wide spectrum photosynapse array with 64k-scale for neuromorphic fusion imaging

Nature Communications
Bio-inspired photosynapse hardware with wide spectrum information fusion imaging and neuromorphic processing is promising for complex environments perception.
Guan-Hua Dun, Jia-He Zhang, Xin-Xing Xie, Ken Qin, Daixuan Wu, Jia-Li Peng, He-Xuan Wang, Zi Wang, Hua-Jing Fang, Dan Xie, He Tian, Yi Yang, Tian-Ling Ren   +12 more
doaj   +1 more source

Static random‐access memory with embedded arithmetic logic units for in‐memory computing and ternary content addressable memory operation

Electronics Letters, 2022
In‐memory computing (IMC) is a novel computing architecture that presents considerable potential in solving the data transmission and energy consumption problems faced by the von Neumann architecture.
Zhiting Lin, Xing Fan, Shuiyue Yu, Chunyu Peng, Qiang Zhao, Xiulong Wu   +5 more
doaj   +1 more source