Results 111 to 120 of about 4,706,350 (310)

Screening for frailty and its association with activities of daily living, cognitive impairment, and falls among community-dwelling older adults in China

BMC Geriatrics
Objectives Frailty is a prevalent geriatric condition that significantly impacts the health of older adults. This study aimed to examine the prevalence of frailty among older Chinese adults aged ≥ 65 years and to assess its association with adverse ...
Dakang Ji, Haijian Guo, Shanhu Qiu, Lirong Dong, Ya Shen, Zhengkai Shen, Jinshui Xu   +6 more
doaj   +1 more source

ECONOMIC ANALYSIS OF ALFALFA INTEGRATED MANAGEMENT PRACTICES [PDF]

Integrated pest management (IMP) initially focused on insect pest control. More recently, IPM encompasses a broader concept of management, one which crosses several disciplinary boundaries.
Berberet, Richard C., Dowdy, Alan K., Stritzke, Jimmie F., Ward, Clement E.   +3 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Integrated Design Tools for Embedded Control Systems [PDF]

, 2001
Currently, computer-based control systems are still being implemented using the same techniques as 10 years ago. The purpose of this project is the development of a design framework, consisting of tools and libraries, which allows the designer to build ...
Broenink, Jan F., Hilderink, Gerald H., Jovanovic, Dusko S.   +2 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Development of the ZJ30/1800DB Automatic Drilling Rig

Shiyou jixie, 2016
To enhance the drilling rig automation,intelligent operation level,and to improve operational safety and the working environment,the ZJ30/1800DB automatic drilling rig has been developed.The rig,configured by automatic pipe handling device like powered ...
Shen Junli, Zhang Youhui, Kang Yunhua, Liu Weiguo, Liu Jing   +4 more
doaj  

Flight propulsion control integration for V/STOL aircraft [PDF]

The goal of the propulsion community is to have the enabling propulsion technologies in place to permit a low risk decision regarding the initiation of a research STOVL supersonic attack fighter aircraft in the mid-1990's.
Mihaloew, James R.
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

STOL Simulation Requirements for Development of Integrated Flight/propulsion Control Systems [PDF]

, 1984
The role and use of simulation as a design tool in developing integrated systems where design criteria is largely unavailable is well known. This paper addresses additional simulation needs for the development of Integrated Flight/Propulsion Control ...
Anderson, D. C., Sanders, K. E., Watson, J. H.   +2 more
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source