Results 131 to 140 of about 2,465,688 (305)

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

open access: yesFEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito   +3 more
wiley   +1 more source

Low-Voltage Distribution Network Loss-Reduction Method Based on Load-Timing Characteristics and Adjustment Capabilities

open access: yesEnergies
The primary contributors to elevated line losses in low-voltage distribution networks are three-phase load imbalances and variations in load peak–valley differentials.
Cheng Huangfu   +3 more
doaj   +1 more source

REMIND-D: A Hybrid Energy-Economy Model of Germany [PDF]

open access: yes
This paper presents a detailed documentation of the hybrid energy-economy model REMIND-D. REMIND-D is a Ramsey-type growth model for Germany that integrates a detailed bottom-up energy system module, coupled by a hard link.
Brigitte Knopf, Eva Schmid, Nico Bauer
core  

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

open access: yesFEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli   +9 more
wiley   +1 more source

Optimized MMC passive impedance shaping method for high frequency oscillation suppression

open access: yesInternational Journal of Electrical Power & Energy Systems
Recent years, there have been several high-frequency oscillation events in modular multilevel converter (MMC) based DC current projects. Considering the wideband oscillation characteristics of this issue, passive MMC impedance shaping methods are ...
Shiqi Yang   +6 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Synergistic Effects of Fly Ash and Oyster Shell Powder in Ternary Low-Carbon Cementitious Materials: Macro–Micro Experimental Studies and Life Cycle Evaluation

open access: yesApplied Sciences
As a result of global urbanization, the construction industry has mainly emitted CO2 from ordinary Portland cement (OPC). Partially replacing cement with supplementary cementitious materials is a widely studied approach for reducing emissions.
Kang-Jia Wang   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy