Results 111 to 120 of about 812,823 (296)

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Faktor Maternal dan Pelayanan Ante Natal Care Terintegrasi pada Kejadian Prematuritas di Puskesmas Wilayah Kota Palangka Raya [PDF]

, 2017
Premature delivery is a risk factor that causes neonatal death. Various attempts were made to reduce the neonatal mortality rate, such as integrated antenatal care.
Legawati, L. (Legawati), Noordiati, N. (Noordiati), Riyanti, R. (Riyanti)   +2 more
core  

Implementing health research through academic and clinical partnerships : a realistic evaluation of the Collaborations for Leadership in Applied Health Research and Care (CLAHRC) [PDF]

, 2011
Background: The English National Health Service has made a major investment in nine partnerships between higher education institutions and local health services called Collaborations for Leadership in Applied Health Research and Care (CLAHRC).
Andrews, Gavin J., Ariss, Steven, Baker, Richard, Burton, Christopher R., Dopson, Sue, Graham, Ian D., Harvey, Gill, Martin, Graham P., McCormack, Brendan, Rycroft-Malone, Jo, Staniszewska, Sophie, Thompson, Carl, DPhil, Wilkinson, Joyce E.   +12 more
core   +6 more sources

Integrated Health Care Delivery for Adolescents Living with and at Risk of HIV Infection:  A Review of Models and Actions for Implementation. [PDF]

AIDS Behav, 2023
Subramanian S, Namusoke-Magongo E, Edwards P, Atujuna M, Chimulwa T, Dow D, Jalil E, Torbunde N, Agot K, Arinaitwe I, Beizer J, Chelwa N, Mbalinda SN, Miti S, Mwangwa F.   +14 more
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Pearls from a Clinician-Researcher in an Integrated Health care Delivery System. [PDF]

Perm J, 2021
Ettinger KM, Ettinger VM, Jaffe MG, Schroeder DA, Lo JC.   +4 more
europepmc   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Implementing social health insurance in Ireland: Report of a meeting and workshop held in Dublin, on December 6th 2010 [PDF]

, 2011
We considered two basic questions, 'Is it possible to implement Social Health Insurance in Ireland?', and 'How can this be done?'. Can Social Health Insurance be implemented in Ireland? Our answer is a very definite yes. Furthermore, there would be many
Crotty, Gerard, De La Harpe, Davida, Drumm, Michael, Groenewegen, Peter, Hardiman, Orla, O'Connor, Maire, Smith, Susan, Staines, Anthony, Sweeney, Mary Rose, Thomas, Steven, White, Martin   +10 more
core  

Outcomes of Adults with Severe Aortic Stenosis Undergoing Urgent or Emergent vs. Elective Transcatheter Aortic Valve Replacement Within an Integrated Health Care Delivery System. [PDF]

Struct Heart, 2023
Slade JJ, Ambrosy AP, Leong TK, Sung SH, Garcia EA, Ku IA, Solomon MD, McNulty EJ, Rassi AN, Lange DC, Philip F, Go AS, Mishell JM.   +12 more
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source