Results 81 to 90 of about 23,332,431 (264)

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng, Lan Li, Qingmei Yang, Meipeng Wu   +3 more
wiley   +1 more source

The Integrated Information Theory Needs Attention

Erkenntnis
Abstract The Integrated Information Theory (IIT) might be our current best bet at a scientific explanation of phenomenal consciousness. IIT focuses on the distinctively subjective and phenomenological aspects of conscious experience.
Azenet Lopez, Carlos Montemayor
openaire   +3 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Estimating the Integrated Information Measure Phi from High-Density Electroencephalography during States of Consciousness in Humans

Frontiers in Human Neuroscience, 2018
The integrated information theory (IIT) proposes a quantitative measure, denoted as Φ, of the amount of integrated information in a physical system, which is postulated to have an identity relationship with consciousness. IIT predicts that the value of Φ
Hyoungkyu Kim, Hyoungkyu Kim, Anthony G. Hudetz, Anthony G. Hudetz, Anthony G. Hudetz, Joseph Lee, George A. Mashour, George A. Mashour, George A. Mashour, UnCheol Lee, UnCheol Lee, the ReCCognition Study Group, Michael S. Avidan, Tarik Bel-Bahar, Stefanie Blain-Moraes, Goodarz Golmirzaie, Ellen Janke, Max B. Kelz, Paul Picton, Vijay Tarnal, Giancarlo Vanini, Phillip E. Vlisides   +21 more
doaj   +1 more source

Measuring the integrated information of a quantum mechanism

, 2023
Originally conceived as a theory of consciousness, integrated information theory (IIT) provides a theoretical framework intended to characterize the compositional causal information that a system, in its current state, specifies about itself. However, it
Robert Prentner, Larissa Albantakis, Ian Durham, Durham, Ian, Prentner, Robert, Albantakis, Larissa   +5 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Approaching Information as an Integrated Field: educating Information Professionals [PDF]

, 2011
Περιέχει το πλήρες κείμενοThis is a brief presentation of the framework and philosophy followed by the Department of Library Science and Information Systems in the development of its new curriculum.

core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Classical Mathematical Integrated Information Theory

, 2021
This paper is an attempt to give mathematical structure to classical integrated information theory by Masafumi Oizumi, Larissa Albantakis, Giulio Tononi, using the definition provided by Giulio Tononi and making few assumptions like the mechanisms are ...
Siddharth Sharma
core   +1 more source