Results 21 to 30 of about 70,085 (217)

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Panoràmica dels sistemes de gestió de biblioteques al segle XXI

BiD: Textos Universitaris de Biblioteconomia i Documentació, 2005
En la darrera dècada s’han consolidat un conjunt de tendències en l’àmbit de la informàtica general que han afectat profundament les biblioteques. La popularització d’Internet, l’aparició de sistemes oberts i interoperables, la consolidació d’entorns ...
Salse i Rovira, Marina
doaj  

On the Clouds: A New Way of Computing

Information Technology and Libraries, 2010
This article introduces cloud computing and discusses the author’s experience “on the clouds.” The author reviews cloud computing services and providers, then presents his experience of running multiple systems (e.g., integrated library systems, content ...
Yan Han
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

RDA and library systems

BiD: Textos Universitaris de Biblioteconomia i Documentació, 2007
L'article planteja el rerefons del desenvolupament de l'RDA (descripció i accés a recursos), un estàndard de metadades de caràcter internacional adreçat a un ample ventall de comunitats de metadades.
Dunsire, Gordon
doaj  

Librarians’ Perceptions About Adoption and Uses of The Integrated Library Software

Indonesian Journal of Educational Research and Technology
The main objective of this study was to investigate the factors that influenced the adoption of Koha-integrated library software by librarians in Sri Lankan universities and libraries and to examine the challenges that were encountered during the ...
N. G.D.A. Jayarathna, H. M.M.N. Herath
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

A Study of the Development Process of Library Software, From Integrated Library System to the Library Services Platform [PDF]

بازیابی دانش و نظام‌های معنایی
IntroductionThe main feature of library software in the era of communication technology was networking and widespread access to library resources. Information science and knowledge specialists have always taken steps to realize the idea of information ...
Elaheh Hassanzadeh Dizaji, Esmat Momeni, Samaneh Nouzar, Maryam Pakdaman Naeini, Nastaran Poursalehi, Zeinab Biranvand, Fatemeh Zarinkamar   +6 more
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Veinticinco años de automatización de bibliotecas en Cataluña

BiD: Textos Universitaris de Biblioteconomia i Documentació, 2006
L’article presenta la història de l’automatització de les biblioteques a Catalunya. S’hi fa un repàs que va des de les primeres biblioteques automatitzades fins a l’actualitat.
Anglada i de Ferrer, Lluís M.
doaj