Results 61 to 70 of about 1,016,597 (325)
Digital information support for concept design [PDF]
, 2010 This paper outlines the issues in effective utilisation of digital resources in conceptual design. Access to appropriate information acts as stimuli and can lead to better substantiated concepts.
Ion, William, Wodehouse, Andrew
core +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
PMB : programari lliure d’automatització de biblioteques
BiD: Textos Universitaris de Biblioteconomia i Documentació, 2006 Es descriuen les característiques del programari lliure de gestió de biblioteques PMB -llicència, requisits i funcionalitats- i s'analitzen les prestacions dels seus mòduls i del seu OPAC.
Russo Gallo, Patricia
doaj
Migration to Alma/Primo: A Case Study of Central Washington University [PDF]
, 2015 This paper describes how Central Washington University Libraries (CWUL) interacted and collaborated with the Orbis Cascade Alliance (OCA) Shared Integrated Library System’s (SILS) Implementation Team and Ex Libris to process systems and data migration ...
Carmen, Julie, Fu, Ping
core +2 more sources
A framework for design engineering education in a global context [PDF]
, 2010 This paper presents a framework for teaching design engineering in a global context using innovative technologies to enable distributed teams to work together effectively across international and cultural boundaries.
Ade Mabogunje +13 more
core +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Twenty-five years of library automation in Catalonia
BiD: Textos Universitaris de Biblioteconomia i Documentació, 2006 L’article presenta la història de l’automatització de les biblioteques a Catalunya. S’hi fa un repàs que va des de les primeres biblioteques automatitzades fins a l’actualitat.
Anglada i de Ferrer, Lluís M.
doaj
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Vint-i-cinc anys d'automatització de biblioteques a Catalunya
BiD: Textos Universitaris de Biblioteconomia i Documentació, 2006 L’article presenta la història de l’automatització de les biblioteques a Catalunya. S’hi fa un repàs que va des de les primeres biblioteques automatitzades fins a l’actualitat.
Anglada i de Ferrer, Lluís M.
doaj