Results 51 to 60 of about 2,865,672 (291)
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
Integrating automated support for a software management cycle into the TAME system [PDF]
, 1989 Software managers are interested in the quantitative management of software quality, cost and progress. An integrated software management methodology, which can be applied throughout the software life cycle for any number purposes, is required. The TAME (
Basili, Victor R., Sunazuka, Toshihiko
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Overview of Integrated Vehicle Management System
Xibei Gongye Daxue Xuebao, 2020 Under the modern high-tech condition, the demand of air combat has been stricter on the combat performance and the integration of fighter, which impels the application of integrated vehicle management technology and makes it become the core technology of
doaj +1 more source
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Communications, 2015 The authors, as a result of their scientific and professional activities, present a concept of a future model for integrated management of risks in plants for production of automobiles and their components for contractors. They introduce the concept of a
Milan Majernik +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Archives of Acoustics, 2013 It is well known that sound absorption and sound transmission properties of open porous materials are highly dependent on their airflow resistance values.
Romina del REY +3 more
doaj
Risk management in the environmental management system of an oil refinery
Journal of Degraded and Mining Lands ManagementSlavneft-YANOS was one of the first in Russia to obtain the ISO 14001 compliance certificate for the Environmental Management System (EMS). This quality standard has the highest requirements for environmental management, environmental protection, and ...
Sophia A Tsareva, Yuri V Tsarev
doaj +1 more source