Results 61 to 70 of about 570,018 (263)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

NECESSITY OR CHALLENGE - INFORMATION SECURITY FOR SMALL AND MEDIUM ENTERPRISES [PDF]

Annals of the University of Petrosani: Economics, 2010
Due to the inadequate mamagement of information securityexpectations and various unexpected information technology incidents, small and mediumenterprises that lose data or have to cope with a lack of data over a certain period of time maylose business ...
CSABA LÁBODI, PÁL MICHELBERGER
doaj  

Retracted: Design of Integrated Management System of IPE Instructional Resources Information Based on Artificial Intelligence Environment. [PDF]

J Environ Public Health, 2023
Environmental And Public Health JO.
europepmc   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Experimental Investigation on the Wells Turbine with Tubercle-Twisting Blade for Performance Enhancement on Oscillating Water Column

Journal of Eta Maritime Science
The Wells turbine is an air turbine in the Oscillating Water Column (OWC) system with lower performance than the Impulse turbine at small diameters. However, the Wells turbine can operate at lower wave heights compared to the Impulse turbine.
Madi Madi, Rahma Yanda, Meida Untoro, Muhamma Gufran Nurendrawan Bangsa   +3 more
doaj   +1 more source

DEVELOPMENT OF THE INTEGRATED SYSTEM OF QUALITY MANAGEMENT AND SAFETY ASSURANCE AT THE CONFECTIONERY ENTERPRISE [PDF]

Техника и технология пищевых производств, 2015
Due to the fact that food products are considered to be potentially dangerous, it is becoming increasingly important for the food industry of all countries to develop and use management systems that ensure food safety for consumers and also provide the ...
Surkov I.V., Gorelikova G.A., Bindyuk V.S.   +2 more
doaj  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Global Performance Index for Integrated Management System: GPI-IMS. [PDF]

Int J Environ Res Public Health, 2021
Silvestri A, Falcone D, Di Bona G, Forcina A, Gemmiti M.   +4 more
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

An Integrated Management System for Noncommunicable Diseases Program Implementation in a Sub-Saharan Setting. [PDF]

Int J Environ Res Public Health, 2021
Miselli MA, Cavallin F, Marwa S, Ndunguru B, Itambu RJ, Mutalemwa K, Rizzi M, Ciccarelli G, Conte S, Taddei S, Azzimonti G, Putoto G, Torelli GF.   +12 more
europepmc   +1 more source