Results 81 to 90 of about 2,846,080 (291)

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Global Performance Index for Integrated Management System: GPI-IMS. [PDF]

Int J Environ Res Public Health, 2021
Silvestri A, Falcone D, Di Bona G, Forcina A, Gemmiti M.   +4 more
europepmc   +1 more source

Barcoding and ILS Migration from Start to Finish: A Case Study

, 2018
This practice-oriented article outlines one institution’s process of implementing both electronic checkout and a new integrated library system (ILS) for an academic library of 187,000 physical items.
Arjona, Beth
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Implementation of Integrated Management System in Order to Enhance Equipment Efficiency

Management Systems in Production Engineering, 2019
The main aim of presented article is to present methodology how sophisticated products as compressor equipment can be considered and analysed as a complex technical system which consists of jointly operating components – a set of hardware, software ...
Zaloga Viliam, Dyadyura Konstiantyn, Rybalka Iryna, Pandova Iveta   +3 more
doaj   +1 more source

An Integrated Management System for Noncommunicable Diseases Program Implementation in a Sub-Saharan Setting. [PDF]

Int J Environ Res Public Health, 2021
Miselli MA, Cavallin F, Marwa S, Ndunguru B, Itambu RJ, Mutalemwa K, Rizzi M, Ciccarelli G, Conte S, Taddei S, Azzimonti G, Putoto G, Torelli GF.   +12 more
europepmc   +1 more source

Information management system: A summary discussion [PDF]

An information management system is proposed for use in the space shuttle sortie, the modular space station, the tracking data relay satellite and associated ground support systems.
Sayers, R. S.
core   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Designing a productive, profitable integrated farming system model with low water footprints for small and marginal farmers of Telangana

Scientific Reports
In the years 2021–2022 and 2022–2023, an experiment was carried out at the IFS Unit, College of Agriculture, PJTSAU, Rajendranagar in order to determine the best one-acre integrated farming system model for Telangana's small and marginal farmers.
Rayapati Karthik, M. Venkata Ramana, Ch. Pragathi Kumari, T. Ram Prakash, M. Goverdhan, D. Saida Naik, Mandapelli Sharath Chandra, M. Santhosh Kumar, Nallagatla Vinod Kumar, L. Peace Raising, Kirttiranjan Baral, Rajan Bhatt, Nadhir Al-Ansari, Khalid M. Elhindi, Mohamed A. Mattar   +14 more
doaj   +1 more source

THE MANAGEMENT OF OCCUPATIONAL HEALTH AND SAFETY IN ROMANIA [PDF]

The management of occupational health and safety constitutes the missing link as concerns the elaboration and implementation of integrated management systems i.e.
Marius Mitrache
core