Results 191 to 200 of about 5,237,372 (315)

INTEGRATED ASSESSMENT MODELLING [PDF]

integrated ...
Richard S.J. Tol
core  

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

IMPACT-4CCS: Integrated Modeling and Prediction Using Ab Initio and Trained Potentials for Collision Cross Sections. [PDF]

J Comput Chem
Farmer C, Medina H.
europepmc   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Integrated modeling of protein and RNA. [PDF]

Brief Bioinform
Liu H, Zhao Y.
europepmc   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Integrated Modeling of Digital-Motor and Clinician-Reported Outcomes Using Item Response Theory: Towards Powerful Trials for Rare Neurological Diseases. [PDF]

CPT Pharmacometrics Syst Pharmacol
Hamdan A, Traschütz A, Beichert L, Chen X, Gagnon C, van de Warrenburg BP, Santorelli FM, Başak N, Coarelli G, Horvath R, Klebe S, PROSPAX consortium, EVIDENCE‐RND consortium, Schüle R, Hooker AC, Synofzik M, Karlsson MO.   +16 more
europepmc   +1 more source

New Methods for Integrated Models of Animal Disease Control [PDF]

Accurate assessments of the epidemiological and economic impacts of an animal disease require the incorporation of feedbacks between disease spread and production incentives. This paper motivates a new modeling framework that is sensitive to the dynamics
Rich, Karl M.
core  

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Integrated Modeling and Target Classification Based on mmWave SAR and CNN Approach. [PDF]

Sensors (Basel)
Wadde C, Routhu G, Clemente-Arenas M, Gummadi SP, Kumar R.   +4 more
europepmc   +1 more source