Results 101 to 110 of about 1,156,952 (310)
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi +5 more
wiley +1 more source
Integrating economic values and catchment modelling [PDF]
Integrated catchment policies are widely used to manage natural resources in Australian catchments. Decision support tools available to aid integrated catchment management are often limited in their integration of environmental processes with socio ...
Bennett, Jeffrey W., Kragt, Marit Ellen
core +1 more source
Estimating the effects of water-induced shallow landslides on soil erosion [PDF]
Rainfall induced landslides and soil erosion are part of a complex system of multiple interacting processes, and both are capable of significantly affecting sediment budgets.
Bosco, Claudio, Sander, Graham
core +1 more source
Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley +1 more source
An integrative framework to combine migratory connectivity and demographic data
Migratory species experience various conditions and events throughout their annual cycle that influence their spatial and demographic dynamics. To understand these dynamics, it is essential to describe the origin and destination of individuals. Migratory
Killian A. Gregory +14 more
doaj +1 more source
An integrated modelling approach for targeted degradation: insights on optimization, data requirements and PKPD predictions from semi- or fully-mechanistic models and exact steady state solutions. [PDF]
Guzzetti S, Morentin Gutierrez P.
europepmc +1 more source
Ordinary differential equation (ODE) based generative models have emerged as a powerful approach for producing high-quality samples in many applications. However, the ODE-based methods either suffer the discretization error of numerical solvers of ODE, which restricts the quality of samples when only a few NFEs are used, or struggle with training ...
Jingjing Wang +4 more
openaire +2 more sources
Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
CRIMSON: An open-source software framework for cardiovascular integrated modelling and simulation. [PDF]
Arthurs CJ +33 more
europepmc +1 more source
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source

