Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Integrated oxygen recovery system [PDF]
Life Systems has conceptualized an innovative Integrated Oxygen Recovery System (IORS) applicable to advanced mission air revitalization. The IORS provides the capability to electrochemically generate metabolic oxygen (O2) and recover O2 from the space ...
Davenport, Ronald J., Lee, M. Gene
core +2 more sources
Commercialising Australia's interstate rail freight transport: Some ownership and investment issues [PDF]
, 1995 The paper addresses the issues of rights of way ownership and application of consistent investment appraisal techniques across modes of transport. There are linkages between ownership, rights of way, competitive strategies and market contestability which
Ferreira, Luis, Williams, Alan W.
core +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Applied Analysis on Electromagnetic Braking in the Vehicle Braking Energy Recovery
Jixie chuandong, 2016 The working principle and characteristic of the braking energy recovery system are introduced.The working principle of automotive electromagnetic braking is introduced.
Tu Kun, He Ren
doaj
Integrated analysis of error detection and recovery [PDF]
An integrated modeling and analysis of error detection and recovery is presented. When fault latency and/or error latency exist, the system may suffer from multiple faults or error propagations which seriously deteriorate the fault-tolerant capability ...
Lee, Y. H., Shin, K. G.
core +1 more source
Recommendations for changes in UK National Recovery Guidance (NRG) and associated guidance from the perspective of Lancaster University's Hull Flood Studies [PDF]
, 2011 This report was commissioned by the Civil Contingencies Secretariat (CCS) following the publication of Lancaster University‟s Hull Flood Project and Hull Children‟s Flood Project.
Deeming, Hugh +2 more
core +1 more source
Feasibility study of a combi-pv panel for greenhouse energy supply and water recovery by nightly radiation towards the sky [PDF]
, 2011 In southern European areas, characterized by high irradiation, the use of water for both evaporative cooling systems and hydroponic fertigation, represents a serious drawback for crop cultivation under cover.
Bibbiani, C. +4 more
core +2 more sources
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Retrofit of Refinery Hydrogen Network Integrated with Light Hydrocarbon Recovery
Chemical Engineering Transactions, 2017 The processing ratio of inferior and heavy oil has been increasing. With the much more stringent environmental regulations, hydrogenation process in the modern refinery has been more widely used.
M. Zhu, C. Deng, X. Feng
doaj +1 more source