Results 81 to 90 of about 4,195,537 (293)

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Building Care in the Heart of the Moment – Exploring the Process of Collaboration for the Making of Flexible Assertive Community Treatment

International Journal of Integrated Care
Introduction: Professional and organisational collaboration of integrated services, like Flexible Assertive Community Treatment (FACT), plays a pivotal role in ensuring continuous and coordinated care for persons with complex mental health needs.
Ulrika Bejerholm, Daniel Lindqvist, Sofie Westling, Elisabeth Argentzell, Annika Lexén, Marcus Knutagård   +5 more
doaj   +1 more source

Retrofit of Refinery Hydrogen Network Integrated with Light Hydrocarbon Recovery

Chemical Engineering Transactions, 2017
The processing ratio of inferior and heavy oil has been increasing. With the much more stringent environmental regulations, hydrogenation process in the modern refinery has been more widely used.
M. Zhu, C. Deng, X. Feng
doaj   +1 more source

A distributionally robust optimization approach for airline integrated recovery under in-flight pandemic transmission risks. [PDF]

Transp Res Part C Emerg Technol, 2023
Xu Y, Wandelt S, Sun X.
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Technical and economic assessment of trash recovery in the sugarcane bioenergy production system

Scientia Agricola, 2013
Mechanized sugarcane (Saccharum spp.) harvest without burning has been increasingly adopted in Brazil, increasing trash availability on the field. This study aims at showing the importance of using an integrated framework tool to assess technical and ...
Terezinha de Fátima Cardoso, Otávio Cavalett, Mateus Ferreira Chagas, Edvaldo Rodrigo de Morais, João Luís Nunes Carvalho, Henrique Coutinho Junqueira Franco, Marcelo Valadares Galdos, Fábio Vale Scarpare, Oscar Antonio Braunbeck, Luis Augusto Barbosa Cortez, Antonio Bonomi   +10 more
doaj   +1 more source

Challenges and solutions for the integrated recovery room planning and scheduling problem during COVID-19 pandemic. [PDF]

Med Biol Eng Comput, 2022
Chaieb M, Sassi DB, Jemai J, Mellouli K.
europepmc   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Cannabidiol’s effectiveness in post-exercise recovery: an integrated systematic review

MHSalud
Objectives: Recovery between physical efforts is essential to achieving optimal performance in sports. Dietary supplements have been proposed to facilitate recovery and performance optimization, including the phytocannabinoid cannabidiol (CBD).
Carmen Villalobos-González, Carlos D. Gómez-Carmona, Braulio Sánchez-Ureña, Christian Azofeifa-Mora, Daniel Rojas-Valverde   +4 more
doaj   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source