Results 201 to 210 of about 365,790 (277)

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Reconsidering Percentile Reporting in Plastic Surgery In-service Examinations: Insights From the Trainee Perspective. [PDF]

Plast Reconstr Surg Glob Open
Zeitouni F, Craig J, Tierney M, Attaluri PK, Rao VK.   +4 more
europepmc   +1 more source

Pengaruh Pengungkapan Elemen-Elemen Integrated Reporting terhadap Nilai Perusahaan pada Perusahaan Properti dan Real Estate Tahun 2019-2022

Muhammad Noor Irfansyah, Syaiful Hifni
openalex   +2 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Data integration report

Report on the use of data integration from satellite imaging spectrometry and multispectral sensors for improving water quality ...
openaire   +3 more sources

What is the meaning of interpregnancy interval after caesarean section for women planning further pregnancies: a mixed method systematic review protocol. [PDF]

Syst Rev
Canty AM, Keedle H, Hennessy A, Makris A.   +3 more
europepmc   +1 more source

An Integrated Approach of Management of Androgenic Alopecia with Homeopathic and Stem Cell Intervention- A Case Report

Armida K P
openalex   +1 more source

Integrated use of contrast-enhanced and grey-scale ultrasound in assigning American College of Radiology Thyroid Imaging–Reporting and Data System scores for characterisation of thyroid nodules: A prospective observational study [PDF]

Ashish Verma, Adith Krishna K, Ishan Kumar, Pramod Kumar Singh, Amrita Kar, Neeraj Agrawal   +5 more
openalex   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Author Response: From Narrative to Navigation: A Translational Roadmap for AI-enabled Early Sepsis Prediction-Comment on Shanmugam et al. [PDF]

Indian J Crit Care Med
Shanmugam H, Airen L, Rawat S.
europepmc   +1 more source