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Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Counting every loss, acting on every risk. [PDF]

open access: yesLancet Reg Health Southeast Asia
Sethi V   +4 more
europepmc   +1 more source

Integrated reporting [PDF]

open access: yes, 2020
Nick Topazio   +5 more
core   +5 more sources

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