Results 101 to 110 of about 19,222,922 (285)
APPLICATION OF GEOGRAPHICAL INFORMATION SYSTEMS FOR A CITY EMERGENCY MANAGEMENT
TASK Quarterly, 1998 This paper presents basic information about GIS and reveals process of creating system application for a city emergency purposes. Traditional and modified rescue processing schemes are presented and compared.
KATARZYNA KOT +2 more
doaj
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Technologies and equipment for efficient drilling rescue
Meitian dizhi yu kantanObjective In China, mining operations are progressively extending to greater depths, with annual tunneling of mine roadways and tunnels nationwide reaching nearly 20000 km. In this context, mine (tunnel) accidents occur frequently, threatening the safety
Ningping YAO +6 more
doaj +1 more source
Software Support for the Integrated Rescue System
, 2020 Martin Dzermansky, Jakub Rak
openaire +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Integrated Rescue System in the Czech Republic [PDF]
Prehospital and Disaster Medicine, 1999 openaire +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Technical equipent in Integrated rescue system
, 2009 Bakalářská práce zpracovává aktuální problematiku používaných technických prostředků v Integrovaném záchranném systému, se zaměřením na hasičské záchranné sbory a zdravotnické záchranné služby. Práce popisuje jednotlivé prvky technického vybavení, včetně
Vlková, Lenka
core +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source