Results 81 to 90 of about 300,999 (301)

Seismic vulnerability assessment of the old city centre of Seixal, Portugal [PDF]

, 2012
The seismic vulnerability assessment of old traditional masonry building stocks, in a seismic risk mitigation perspective, is truly essential not only for buildings with recognized historical and patrimonial value, but also, in relation to regular ...
Costa, A., Ferreira, T., Mendes da Silva, J. A. R., Varum, H., Vicente, R.   +4 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Safety management at the (micro)regional level [PDF]

, 2010
Global and domestic Czech experience shows the growing importance of safety management at the beginning of the 21st century. Area safety issues are currently well solved at the state and regional level in the Czech Republic, but there are still missing ...
Horčička, Aleš
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Adaptive service discovery on service-oriented and spontaneous sensor systems [PDF]

, 2012
Service-oriented architecture, Spontaneous networks, Self-organisation, Self-configuration, Sensor systems, Social patternsNatural and man-made disasters can significantly impact both people and environments.
Antonopoulos, Nikolaos, Li, Jianxin, Liu, Lu, Wu, Kaigu, Xu, Jie   +4 more
core   +1 more source

Developing an Efficient DMCIS with Next-Generation Wireless Networks [PDF]

, 2006
The impact of extreme events across the globe is extraordinary which continues to handicap the advancement of the struggling developing societies and threatens most of the industrialized countries in the globe.
Hong, Choong Seon, Pathan, Al-Sakib Khan
core   +2 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Design and Development of Police Emergency Response Drone System PERDS [PDF]

EPJ Web of Conferences
This paper presents the design, development and implementation of the Police Emergency Response Drone System (PERDS), It is an integrated solution created to support the police during emergencies, like kidnappings and threats against women.
Prasad R Hem, U Lithesh, G Shanmugasundar   +2 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source