Results 71 to 80 of about 76,631 (254)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Design of a Solar Energy Storage Emergency Rescue Backpack Integrated With Global Positioning System, Light Emitting Diode, and a Heating Module

open access: yesEnergy Science & Engineering
Mountain climbing often involves sudden weather changes, group separation, and mobile device battery depletion, which can lead to life‐threatening emergencies.
Jian‐Sheng Huang, Li‐Chin Shih
doaj   +1 more source

A modular casing while drilling rig for large-diameter horizontal boreholes for underground rescue

open access: yesMeitian dizhi yu kantan
ObjectiveOperations in a narrow space pose a challenge to rescue in the case of the collapse of mine roadways or tunnels. To address this challenge, this study developed a modular rescue casing while drilling (CwD) rig system for horizontal boreholes ...
Dong FAN   +6 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Progress and prospect of life information detection technology for trapped people in mine drilling rescue

open access: yesMeitan kexue jishu
Life information detection technology, as the primary means of search and rescue at disaster sites, is essential for rescue operations due to its capability for safe, efficient, and accurate identification of trapped personnel.
Hu WEN   +5 more
doaj   +1 more source

Application of “one network one station” wireless communication system in coal mine

open access: yesGong-kuang zidonghua, 2015
For problems of disperse management and difficult maintenance of each informatization system in Shendong Coal Mine, as well as difficult recovering and inconvenient emergency rescue after accidents, a “one network one station” wireless communication ...
WANG Haijun, REN Ze
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Construction of karst cave rescue system: A case study of Guizhou Province

open access: yesCarsologica Sinica
Since the 1980s, with the development of joint spelunking activities between China and other countries, modern spelunking activities and techniques have been introduced and gradually promoted in China. Spelunking is now emerging as a popularized activity,
Shuwen LUO   +14 more
doaj   +1 more source

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