Results 51 to 60 of about 76,528 (254)

Multimodality robotic systems: Integrated combined legged-aerial mobility for subterranean search-and-rescue

open access: yesRobotics and Autonomous Systems, 2022
This work presents a field-hardened autonomous multimodal legged-aerial robotic system for subterranean exploration, extending a legged robot to be the carrier of an aerial platform capable of a rapid deployment in search-and-rescue scenarios. The driving force for developing such robotic configurations are the requirements for large-scale and long ...
Björn Lindqvist   +7 more
openaire   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Design of coal mine emergency rescue auxiliary decision system based on emergency plan

open access: yesGong-kuang zidonghua
In the coal mine emergency rescue auxiliary decision system, there are problems such as insufficient application of emergency plans, low application efficiency, and poor execution of rescue plans generated by the system.
GAO Hongbo
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Design of Emergency Communication Security System of Coal Mine

open access: yesGong-kuang zidonghua, 2012
The paper proposed a design scheme of emergency communication security system of coal mine. The system's core namely emergency rescue software platform integrates underground broadcast telephone, PHS, WiFi mobile phone, dispatching telephone, underground
QIAN Jian-sheng   +2 more
doaj  

Research and Application of the 3D Comprehensive Integrated Mine Management System

open access: yesChemical Engineering Transactions, 2016
The paper discussed the design objectives and implementation technique of the comprehensive integrated mine management system based on integration and the 3D comprehensive integrated technology.
P. Wang
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Development of the Use of Unmanned Aerial Vehicles (UAVs) in Emergency Rescue in China

open access: yesRisk Management and Healthcare Policy, 2021
Tao Li, Haitao Hu School of Law, Hebei University of Economics and Business, Shijiazhuang, Hebei, People’s Republic of ChinaCorrespondence: Tao LiSchool of Law, Hebei University of Economics and Business, Xuefu Road No. 47, Shijiazhuang, 050061, People’s
Li T, Hu H
doaj  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

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