Results 171 to 180 of about 298,694 (309)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Maritime Response and Emergency Care for Irregular Migrants: Experiences of Spanish Rescue Professionals. [PDF]

open access: yesHealthcare (Basel)
Jiménez-Lasserrotte MDM   +5 more
europepmc   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Urban flood disaster prevention, control, and rescue using edge computing and the resilience concept. [PDF]

open access: yesSci Rep
Shuiquan L   +6 more
europepmc   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

open access: yesFEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel   +8 more
wiley   +1 more source

Implementation of a hospital-wide EHR-integrated antibiotic challenge order set. [PDF]

open access: yesAntimicrob Steward Healthc Epidemiol
Hoffmann W   +4 more
europepmc   +1 more source

INTEGRATION OF MULTIPLE UNMANNED SYSTEMS IN AN URBAN SEARCH AND RESCUE ENVIRONMENT

open access: yes, 2013
In view of the local, regional and global security trends over the past decade, the threats of disaster to the populace inhabiting urbanized areas are real and there is a need for increased vigilance. There can be multiple causes for urban disaster natural disasters, terrorist attack and urban warfare are all viable. This thesis focused on the event in
openaire   +1 more source

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