Results 61 to 70 of about 6,158,970 (292)

A dataset for climate, land, energy and water systems modelling in Lao PDRZenodo

Data in Brief
Policymaking often treats economic and resource sectors in isolation of one another, neglecting to consider the interconnections between a country’s climate, land, energy and water (CLEW) systems.
Annie Flint Smith, Kane Alexander, Fernando A. Plazas-Niño, Mark Howells   +3 more
doaj   +1 more source

A research agenda for malaria eradication: modeling.

PLoS Medicine, 2011
Malaria modeling can inform policy and guide research for malaria elimination and eradication from local implementation to global policy. A research and development agenda for malaria modeling is proposed, to support operations and to enhance the broader
malERA Consultative Group on Modeling
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Incorporating Humans in Integrated Ecosystem Assessments [PDF]

Humans are increasingly considered more than simply “part of the ecosystem” by natural scientists and natural resource managers. However, the integration of economic and social sciences into Integrated Ecosystem Assessments (IEAs) is advancing at ...
Kasperski, Steve
core   +3 more sources

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Comparative Analysis of Abattoir-Based Measures and On-Farm Pig Welfare Indicators in Italian Fattening Heavy Pigs

Veterinary Sciences
Animal welfare monitoring is essential in pig production. On-farm animal welfare (AW) assessments may provide a comprehensive overview but are resource-intensive.
Lucia Scuri, Matteo Recchia, Federico Scali, Claudia Romeo, Antonio Marco Maisano, Giovanni Santucci, Camilla Allegri, Marta Masserdotti, Miriam Tenuzzo, Adriana Ianieri, Sergio Ghidini, Giovanni Loris Alborali   +11 more
doaj   +1 more source

Assessment for Complex Learning Resources: Development and Validation of an Integrated Model

International Journal of Emerging Technologies in Learning (iJET), 2013
Todayâ??s e-learning systems meet the challenge to provide interactive, personalized environments that support self-regulated learning as well as social collaboration and simulation. At the same time assessment procedures have to be adapted to the new learning environments by moving from isolated summative assessments to integrated assessment forms ...
Gudrun Wesiak, Mohammad Al-Smadi, Margit Höfler, Christian Gütl   +3 more
openaire   +3 more sources

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source