Results 111 to 120 of about 382,780 (281)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Modelling of integrated scheduling problem of capacitated equipment systems with a multi-lane road network. [PDF]

PLoS One, 2021
Luan D, Zhao M, Zhao Q, Wang N.
europepmc   +1 more source

Integrated Workshop Schedule [PDF]

2021 International Conference on Computer Communications and Networks (ICCCN), 2021
openaire   +1 more source

Scheduling revisited workstations in integrated-circuit fabrication [PDF]

The cost of building new semiconductor wafer fabrication factories has grown rapidly, and a state-of-the-art fab may cost 250 million dollars or more.
Kline, Paul J.
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Collaborative Optimization of Oil Blending and Distribution in Refinery Based on Variable-driven Method

Journal of Chemical Engineering of Japan
Collaborative optimization has received much attention from both research and industry communities for its significant profits. However, the current researches primarily concentrate on optimizing individual subprocesses of refinery operations.
Yuandong Chen, Zihan Lin, Jinhao Pang, Yuchen Gou, Shaofeng Zheng, Dewang Chen   +5 more
doaj   +1 more source

Scheduling lessons learned from the Autonomous Power System [PDF]

The Autonomous Power System (APS) project at NASA LeRC is designed to demonstrate the applications of integrated intelligent diagnosis, control, and scheduling techniques to space power distribution systems.
Ringer, Mark J.
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Effective algorithms for integrated scheduling of handling equipment at automated container terminals [PDF]

In this paper we consider the problem of integrated scheduling of various types of handling equipment at an automated container terminal, where the objective is to minimize the makespan of the schedule.
Meersmans, P.J.M., Wagelmans, A.P.M.
core   +1 more source