Results 161 to 170 of about 63,403 (312)
Integrated Scheduling and Capacity Planning with Considerations for Patients' Length-of-Stays. [PDF]
Prod Oper Manag, 2019 Truong VA, Wang X, Liu N.
europepmc +1 more source
An optimal-control based integrated model of supply chain
Problems of supply chain scheduling are challenged by high complexity, combination of continuous and discrete processes, integrated production and transportation operations as well as dynamics and resulting requirements for adaptability and stability ...
Ivanov, Dmitry
core
A branch-and-bound algorithm for stable scheduling in single-machine production systems. [PDF]
Robust scheduling aims at the construction of a schedule that is protected against uncertain events. A stable schedule is a robust schedule that will change little when variations in the input parameters arise.
Herroelen, Willy, Leus, Roel
core
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Integrated Workshop Schedule [PDF]
2019 28th International Conference on Computer Communication and Networks (ICCCN), 2019 openaire +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
A survey of variants and extensions of the resource-constrained project scheduling problem [PDF]
The resource-constrained project scheduling problem (RCPSP) consists of activities that must be scheduled subject to precedence and resource constraints such that the makespan is minimized.
Hartmann, Sönke, Briskorn, Dirk
core
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Make-to-Order Integrated Scheduling and Distribution [PDF]
Proceedings of the Twenty-Seventh Annual ACM-SIAM Symposium on Discrete Algorithms, 2015 Yossi Azar +3 more
openaire +1 more source