Results 141 to 150 of about 35,694,027 (314)

Een archeologisch bureauonderzoek (BO)

, 2017
Een archeologisch bureauonderzoek ...
EARTH Integrated Archaeology B.V.
core   +1 more source

HERODOTUS: An Educational Site as an Integral Part of a Study Book.

, 1996
In the Netherlands there is an on-going process of restructuring education. Secondary education is nowbeing restructured into a basic level (the first two/three years) and an upper level (the last two/threeyears). The leading idea behind the upper level is the so-called 'study home' concept.
de Vries, Sjoerd A., Donker, Henk
openaire   +2 more sources

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Proceedings of the Integrated Ocean Drilling Program 311: Cascadia Margin Gas Hydrates

, 2006
<p>A transect of four sites was drilled across the northern Cascadia margin during Integrated Ocean Drilling Program Expedition 311 to study the occurrences and formation of gas hydrate in accretionary complexes.
Wang, Jiasheng, Tréhu, Anne M., Malinverno, Alberto, Kaneko, Masanori, Pohlman, John, Malone, Mitchell J., Hashimoto, Yoshitaka, Blanc-Valleron, Marie M., Riedel, Michael, Long, Philip E., Myers, Greg, Palekar, Leena D., Holland, Melanie, Collett, Timothy S., Akiba, Fumio, Yoshioka, Hideyoshi, Ellis, Michelle, Heuer, Verena, Kim, Ji-Hoon, Jackson, Peter D., Torres, Marta E., Schultheiss, Peter, Wortmann, Ulrich G., Kastner, Miriam, Kitajima, Hiroko, Teichert, Barbara, Higashi, Yosuke, Guèrin, Gilles   +27 more
core   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Archeologisch onderzoek naar laat 19e- en vroeg 20e-eeuws vondstmateriaal uit Arnhem

, 2017
Archeologisch onderzoek naar laat 19e- en vroeg 20e-eeuws vondstmateriaal uit Arnhem; een reconstructie van materiële stadscultuur omstreeks ...
EARTH Integrated Archaeology B.V.
core   +1 more source

Booronderzoek Natte Natuurparel Broekhuizerbroek EARTH Integrated Archaeology rapport 213

In opdracht van Waterschap Limburg heeft EARTH Integrated Archaeology B.V. in april 2022 een verkennend booronderzoek (IVO-O) uitgevoerd in een plangebied in Swolgen langs de Boabelsche Loop. Aanleiding voor het onderzoek is de geplande herinrichting van
EARTH Integrated Archaeology BV
core   +2 more sources

Governing Integrated Health and Social Care: An Analysis of Experiences in Three European Countries

International Journal of Integrated Care
Purpose: Achieving greater health and social care integration is a policy priority in many countries, but challenges remain. We focused on governance and accountability for integrated care and explored arrangements that shape more integrated delivery ...
Josephine Exley, Rebecca Glover, Martha McCarey, Sarah Reed, Anam Ahmed, Hubertus Vrijhoef, Tommaso Manacorda, Concetta Vaccaro, Francesco Longo, Ellen Stewart, Nicholas Mays, Ellen Nolte   +11 more
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source