Results 161 to 170 of about 609,637 (218)

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Different approaches to persistent and long-standing persistent atrial fibrillation ablation using pulsed field ablation: impact of procedural workflows on arrhythmia termination. [PDF]

open access: yesEuropace
Dello Russo A   +16 more
europepmc   +1 more source

Distinct mechanisms decommission redundant enhancers to facilitate phenotypic evolution. [PDF]

open access: yesSci Adv
Said-Ahmad A   +6 more
europepmc   +1 more source

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