Results 111 to 120 of about 5,732,396 (306)
A national health information strategy for Malta [PDF]
, 1993 In 1992 a national health information strategy was developed jointly by the Department of Health and the Information Systems Division. A detailed strategy study report was compiled, with recommendations for the development of a number of information ...
Agius Muscat, Hugo, Westwood, M.
core
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
Mortality Related to Nonalcoholic Fatty Liver Disease Is Increasing in the United States
Hepatology Communications, 2019 Population‐level nonalcoholic fatty liver disease (NAFLD) death rate data are sparse. We described death rates for adults with NAFLD in the United States using mortality data from the National Vital Statistics System multiple‐cause mortality data (2007 ...
James M. Paik +5 more
doaj +1 more source
A Modular and Flexible Architecture for an Integrated Corpus Query System [PDF]
, 1994 The paper describes the architecture of an integrated and extensible corpus query system developed at the University of Stuttgart and gives examples of some of the modules realized within this architecture. The modules form the core of a corpus workbench.
Christ, Oliver
core +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Environmental science applications with Rapid Integrated Mapping and analysis System (RIMS) [PDF]
, 2016 The Rapid Integrated Mapping and analysis System (RIMS) has been developed at the University of New Hampshire as an online instrument for multidisciplinary data visualization, analysis and manipulation with a focus on hydrological applications.
Gordov, E. +4 more
core +2 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
A large scale software system for simulation and design optimization of mechanical systems [PDF]
The concept of an advanced integrated, networked simulation and design system is outlined. Such an advanced system can be developed utilizing existing codes without compromising the integrity and functionality of the system.
Dopker, Bernhard, Haug, Edward J.
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Mars integrated transportation system multistage Mars mission [PDF]
In accordance with the objective of the Mars Integrated Transport System (MITS) program, the Multistage Mars Mission (MSMM) design team developed a profile for a manned mission to Mars.
core +1 more source