Results 111 to 120 of about 5,698,656 (287)

A selection principle of submodule switching state vectors for switching frequency reduction in voltage self‐balancing half‐bridge modular multilevel converters

open access: yesIET Power Electronics
The problem of submodule switching frequency reduction in half‐bridge modular multilevel converters (HB‐MMCs) with capacitor voltage self‐balancing control is considered and explored in this paper.
Yiyuan Zhou   +4 more
doaj   +1 more source

Rotational Doppler Signal Classification Based on Support Vector Machine

open access: yesPhotonics
The rotational Doppler effect (RDE) has been playing a vital role in the detection of rotational motion in recent years. However, the results obtained from this detection method are easily influenced by the detection conditions.
Song Qiu, Jin Zheng, Minghui Xiong
doaj   +1 more source

Long-Term Voltage Stability Assessment of an Integrated Transmission Distribution System

open access: yes, 2017
Long-term voltage stability assessment (VSA) of independent transmission (T-VSA) and distribution (D-VSA)systems have been studied since long to estimate load margins. However, their impacts on each other have been neglected due to simplified assumptions
Ajjarapu, Venkataramana, Singhal, Ankit
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Mortality Related to Nonalcoholic Fatty Liver Disease Is Increasing in the United States

open access: yesHepatology Communications, 2019
Population‐level nonalcoholic fatty liver disease (NAFLD) death rate data are sparse. We described death rates for adults with NAFLD in the United States using mortality data from the National Vital Statistics System multiple‐cause mortality data (2007 ...
James M. Paik   +5 more
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

A large scale software system for simulation and design optimization of mechanical systems [PDF]

open access: yes
The concept of an advanced integrated, networked simulation and design system is outlined. Such an advanced system can be developed utilizing existing codes without compromising the integrity and functionality of the system.
Dopker, Bernhard, Haug, Edward J.
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Reliability studies of integrated modular engine system designs [PDF]

open access: yes
A study was performed to evaluate the reliability of Integrated Modular Engine (IME) concepts. Comparisons were made between networked IME systems and non-networked discrete systems using expander cycle configurations.
Hardy, Terry L., Rapp, Douglas C.
core   +1 more source

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