Results 81 to 90 of about 35,067 (308)

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Ultra-Wideband Asymmetric Impedance Transformer Design for High-Power Amplifier MMICs [PDF]

Journal of Electromagnetic Engineering and Science
In this study, an asymmetric impedance transformer is proposed for broadband high-power amplifier (HPA) monolithic microwave-integrated circuits (MMICs).
Jihoon Kim
doaj   +1 more source

The alchemical integral transform revisited

The Journal of Chemical Physics
We recently introduced the Alchemical Integral Transform (AIT), enabling the prediction of energy differences, and guessed an ansatz to parameterize space r in some alchemical change λ. Here, we present a rigorous derivation of AIT’s kernel K and discuss the parameterization r(λ) in n dimensions, i.e., necessary conditions, mathematical freedoms, and ...
Simon León Krug, O. Anatole von Lilienfeld   +1 more
openaire   +3 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

SSTAF: Spatial-Spectral-Temporal Attention Fusion Transformer for Motor Imagery Classification

IEEE Access
Brain–computer interfaces (BCI) in electroencephalography (EEG)-based motor imagery classification offer promising solutions in neurorehabilitation and assistive technologies by enabling communication between the brain and external devices ...
Ummay Maria Muna, Md Mehedi Hasan Shawon, Md Jobayer, Sumaiya Akter, Saifur Rahman Sabuj   +4 more
doaj   +1 more source

Power Quality Improvement and LVRT Capability Enhancement of Wind Farms by Means of an Inductive Filtering Method

Energies, 2016
Unlike the traditional method for power quality improvement and low-voltage ride through (LVRT) capability enhancement of wind farms, this paper proposes a new wind power integrated system by means of an inductive filtering method, especially if it ...
Yanjian Peng, Yong Li, Zhisheng Xu, Ming Wen, Longfu Luo, Yijia Cao, Zbigniew Leonowicz   +6 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Multi-Branch Residual Multiscale CNN Based Power Transformer Fault Diagnosis on Vibration Signal

CSEE Journal of Power and Energy Systems
Status of the transformer is highly associated with safe and stable operation of the whole power system. Since the vibration signal is generated along with operation of the transformer and can indicate change of equipment operation status in real-time ...
Binwen Zhang, Fei Jiao, Jie Tong, Yuanpeng Tan, Zhonghao Zhang, Shuang Lin   +5 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source