Results 51 to 60 of about 430,197 (267)
Integrable systems via polynomial inverse integrating factors
The authors study the center problem for planar ordinary differential equations of the form \[ x'=-y+X_s(x,y),\qquad y'=x+Y_s(x,y), \] where \(X_s\) and \(Y_s\) are homogeneous polynomials of degree \(s.\) These systems write in polar coordinates as \(r'=P_s(\varphi)r^s,\) \(\varphi'=1+Q_s(\varphi)r^{s-1}\), where \[ \begin{aligned} P_s(\varphi)&= R_{s+
Chavarriga, J., Giné, J., Grau, M.
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Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley +1 more source
Finding Liouvillian First Integrals of Rational ODEs of Any Order in Finite Terms
It is known, due to Mordukhai-Boltovski, Ritt, Prelle, Singer, Christopher and others, that if a given rational ODE has a Liouvillian first integral then the corresponding integrating factor of the ODE must be of a very special form of a product of ...
Yuri N. Kosovtsov
doaj
Integrating Factor Methods as Exponential Integrators [PDF]
Recently a lot of effort has been made in the construction and implementation of a class of methods called exponential integrators. These methods are preferable when one has to deal with stiff and highly oscillatory semilinear problems, which often arise after spatial discretization of Partial Differential Equations (PDEs).
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Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Factoring multivariate integral polynomials [PDF]
AbstractWe present an algorithm to factorize polynomials in several variables with integral coefficients that is polynomial-time in the degrees of the polynomial to be factored, for any fixed number of variables. Our algorithm generalizes the algorithm presented by Lenstra, Lenstra Jr. and Lovász (1982) to factorize integral polynomials in one variable.
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Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source

