Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande +11 more
wiley +1 more source
Integration of the Chimp Optimization Algorithm and Rule-Based Energy Management Strategy for Enhanced Microgrid Performance Considering Energy Trading Pattern [PDF]
Mukhtar Fatihu Hamza +2 more
openalex +1 more source
Morphological Integration at 50: Patterns and Processes of Integration in Biological Anthropology [PDF]
Campbell Rolian, Katherine E. Willmore
openalex +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Trans Pacific Stategic Economic Partnership With Japan, South Korea and China Integrate: General Equilibrium Approach [PDF]
Emmanuel Emmanuel
openalex +1 more source
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard +12 more
wiley +1 more source
A circular waste bioeconomy development model in the Ecuadorian fishery industry: the impact of government strategy on supply chain integration and smart operations [PDF]
Yeneneh Tamirat Negash +4 more
openalex +1 more source
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Digital inclusion and urban-rural integration: Mechanisms and regional heterogeneity in China. [PDF]
Qiu X, Yu M, Chen X.
europepmc +1 more source
Structured Matrix Completion with Applications to Genomic Data Integration
Tianxi Cai, Tommaso Cai, Anru R. Zhang
openalex +2 more sources

