Results 51 to 60 of about 11,236,978 (375)

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

Elementary Integration of Superelliptic Integrals [PDF]

open access: yesProceedings of the 2021 International Symposium on Symbolic and Algebraic Computation, 2021
Consider a superelliptic integral $I=\int P/(Q S^{1/k}) dx$ with $\mathbb{K}=\mathbb{Q}( )$, $ $ a primitive $k$th root of unity, $P,Q,S\in\mathbb{K}[x]$ and $S$ has simple roots and degree coprime with $k$. Note $d$ the maximum of the degree of $P,Q,S$, $h$ the logarithmic height of the coefficients and $g$ the genus of $y^k-S(x)$.
openaire   +3 more sources

The Effect of Headquarter Integration Mechanisms on Subsidiaries' New Product Success: From Control to Coordination Mechanism [PDF]

open access: yes, 2007
New product launching (NPL) to the local market by subsidiary managers is a strategic activity, which requires organizational supports from MNC global network. The NPL activity is marked by high level of uncertainty, risk, and market failure.
Firmanzah, F. (Firmanzah)
core  

Evaluating the integration of supply chain information systems: A case study [PDF]

open access: yes, 2004
Supply chain management (SCM) is the integrated management of business links, information flows and people. It is with this frame of reference that information systems integration from both intra- and inter-organisational levels becomes significant ...
Bartezzaghi   +30 more
core   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

open access: yesFEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan   +2 more
wiley   +1 more source

Design and Motion Simulation of a Soft Robot for Crawling in Pipes

open access: yesApplied Bionics and Biomechanics, 2023
In recent years, soft pipeline robot, as a new concept, is proposed to adapt to tunnel. The soft pipeline robots are made of soft materials such as rubber or silicone.
Zhang Yu   +5 more
doaj   +1 more source

Separation/Integration [PDF]

open access: yes, 2014
This programme is built around David C Johnson’s 4-channel tape piece Telefun, realised in the WDR Studio for Electronic Music, Cologne. Gemini 8 is a new work by Sean Williams for Grey Area based on NASA's Gemini missions of the 1960s which paved the ...
Williams, Sean
core  

C‐mannosylation promotes ADAMTS1 activation and secretion in human testicular germ cell tumor NEC8 cells

open access: yesFEBS Letters, EarlyView.
C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi   +5 more
wiley   +1 more source

Evaluation of the Neuroprotective Potential of Sutherlandia frutescens in a Rotenone-Induced Rat Model of Parkinson’s Disease

open access: yesBehavioural Neurology
Sutherlandia frutescens (SF) is a plant used traditionally in South Africa for various health conditions, including neurological disorders. Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by the degeneration of ...
Lilit Darbinyan   +5 more
doaj   +1 more source

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