Results 61 to 70 of about 1,713,861 (267)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Marcos do desenvolvimento infantil em crianças com necessidades de saúde especiais: relato de uma educação em saúde

open access: yesExtensio: Revista Eletrônica de Extensão
Relatar a experiência de aplicar uma estratégia de educação em saúde sobre os marcos do desenvolvimento infantil, com acompanhantes de crianças com anomalias congênitas e hospitalizadas por longo período de tempo.
Maria Graciana da Silva Felipe   +3 more
doaj   +1 more source

Ohmic Contacts With Ultra-Low Optical Loss on Heavily Doped n-Type InGaAs and InGaAsP for InP-Based Photonic Membranes

open access: yesIEEE Photonics Journal, 2016
In this paper, we present significant reductions of optical losses and contact resistances in AgGe-based ohmic contacts to InP membranes. Due to the high solubility of Si in InGaAs and InGaAsP, heavily doped n-type contact layers are grown on InP wafers.
L. Shen   +6 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

A classifier-assisted evolutionary algorithm with knowledge transfer for expensive multitasking problems

open access: yesComplex & Intelligent Systems
Surrogate-assisted evolutionary algorithms provide an effective means for complex and computationally expensive optimization problems. However, due to the scarcity of training samples, the prediction accuracy of frequently-used regression surrogate ...
Min Hu   +6 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

A flexible impedance-based microsystem for multi-parameter sensing in ionic solutions

open access: yesMicrosystems & Nanoengineering
We present a flexible multi-sensor (FMS) microsystem for simultaneous measurement of flow, temperature, and ionic conductivity in liquid environments.
Haoxin Hu   +5 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

A universal and versatile terahertz field manipulation mechanism by manipulating near-infrared phases with a dislocation scheme

open access: yesNature Communications
This paper presents a universal and versatile terahertz (THz) wavefront-phase manipulation by manipulating the two-dimensional phases of the near-infrared pulses.
Qinggang Lin   +11 more
doaj   +1 more source

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