Results 101 to 110 of about 538,303 (266)

RESEARCH-AND-PRODUCTION ASSOCIATION: SPECIFICITY OF EFFECTS OF INTEGRATION

Вестник университета, 2019
The aim of the work is the formalization of the basic directions of manifestations of effects from the integration of high-tech enterprises in the research-and-production association.
A. Voit
doaj  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

RESEARCH-AND-PRODUCTION ASSOCIATION: SPECIFICITY OF EFFECTS OF INTEGRATION

Вестник университета, 2016
The aim of the work is the formalization of the basic directions of manifestations of effects from the integration of high-tech enterprises in the research-and-production association.
A. Voit
doaj  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Supply chain resource integration method under 4PL mode based on associated data

Journal of Applied Science and Engineering
The relevance of power supply chain resources is a key factor affecting the hit rate of resource integration. Therefore, a 4PL mode based supply chain resource integration method based on associated data is proposed. Firstly, analyze the functions of the
Huayu Chu, Lichong Cui, Yuejia Li, Lei Su, Yanyang Fu, Yuxiang Wang   +5 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

The Association Policies and Economic Integration of the Republic of Moldova into the EU and their Alternatives

EIRP Proceedings, 2016
The policies and decisions of association and economic integration of the Republic of Moldova into the European economic social system have a pseudo-scientific, contradictory, fragmentary character.
Gheorghe Rusu, Mihai Bumbu, Cernăuţanu Igor   +2 more
doaj  

Association of social integration with cognitive function trajectories among Chinese older adults: evidence from the China health and retirement longitudinal study (CHARLS)

Frontiers in Aging Neuroscience
BackgroundThe prevalence of cognitive impairment among older adults remains high. It has been proven that social integration is related to cognitive function.
Amu Mose, Yanhong Chen, Xiaoshuang Tan, Qingman Ren, Xiaohui Ren   +4 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source