Results 61 to 70 of about 538,303 (266)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Implementation of a community-based LC-UV drug checking service: promising preliminary findings on feasibility and validity

Harm Reduction Journal
Background The increasing diversity of psychoactive substances on the unregulated drug market poses significant health, psychological, and social risks to people who use drugs (PWUD). To address these risks, various harm reduction (HR) policies have been
Nicolas Fabresse, Eurydice Papias, Alma Heckenroth, Victor Martin, Daniel Allemann, Perrine Roux   +5 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Convergence Modelling in International Integration Associations

Bulletin of the South Ural State University. Series "Mathematical Modelling, Programming and Computer Software", 2020
V.V. Krivorotov1, E.S. Fediai2, O.Yu. Ivanova3, O.Yu. Polyakova3 1Ural Federal University, Ekaterinburg, Russian Federation 2South Ural State University, Chelyabinsk, Russian Federation 3Research Centre for Industrial Development Problems of NAS of Ukraine, Kharkov, Ukraine E-mails: v_krivorotov@mail.ru, fediaies@susu.ru, laptevaou@gmail.com, polya_o ...
Krivorotov, V. V., Fediai, E. S., Ivanova, O. Y., Polyakova, O. Y.   +3 more
openaire   +3 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

EMPIRICAL TEST OF THE INTEGRATION POTENTIAL OF UKRAINE’S COMPETITIVE POWER IN THE EVENT OF POSSIBLE ACCESSION TO THE EU [PDF]

Akademičnij Oglâd
Modern integration priorities for Ukraine necessitate defining and measuring its competitive power (CP) as an EU candidate country. One of the key objectives of competitive policy is identifying the factors that can enhance Ukraine’s CP, thereby ...
Olena Zayats, Olena Pryiatelchuk, Maryna Korol, Pavlo Dziuba   +3 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Eigenfunction expansions associated with an integral operator [PDF]

Transactions of the American Mathematical Society, 1965
Here, a is a real constant between zero and one, and, at least in the learning theoretical application, k(x) is a probability density. It has been conjectured that under reasonable hypotheses the eigenfunctions of K are complete (in L2, say). If this were the case, it would come as something of a surprise, for in the two extreme cases a = 0 and a = 1 ...
openaire   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source