Results 151 to 160 of about 17,350,420 (313)

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

FEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

Community organization guides standardization, adaptability, and innovation: lessons from peer support in the Shanghai Integration Model. [PDF]

Transl Behav Med, 2023
Evans M, Liu Y, Wu X, Cai C, Tang PY, Maggy Coufal M, Qian Y, Fisher EB, Jia W.   +8 more
europepmc   +1 more source

Research on Field Device Integration Model

, 2010
Each field device contains a great deal of automation control information, which is used for different stages of software tools throughout a device's life cycle from the configuration towards operation, maintenance, and asset management. By analyzing
Dan YG(单玉刚), Wang H(王宏)
core  

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Sub-series 2: Publications

, 2004
Bimonthly magazine discussing topics related to aviation and model airplane engines including collecting, restoring, maintaining, and identifying engines, along with ...
The Model Museum, Dannels, Timothy J.
core   +1 more source

Retracted: Management Strategy of Alzheimer's Patients under the Medical-Care Integration Model Based on Big Data Evaluation. [PDF]

Biomed Res Int, 2023
International BR.
europepmc   +1 more source

Models for model integration

, 2017
This is a presentation given at the Crops in silico 2nd Annual Symposium and Workshop, Oxford, UK, 27 June 2017. It covers some ideas about different types of models and how they can be put together using frameworks, as well as how one specific tool, the Parsl python parallel scripting library, can be used to assemble and execute loosely-coupled ...
openaire   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The Cancer Genomic Integration Model for Symptom Science (CGIMSS): A Biopsychosocial Framework. [PDF]

Biol Res Nurs, 2023
Grayson SC, Cummings MH, Wesmiller S, Bender C.   +3 more
europepmc   +1 more source

Paris on Stage: 1889-1914 [exhibition]; Vespasienne (pissoir) Model

, 2013
Information label with photograph of original, in situ; Scale model, part of the Paris on Stage: 1889-1914 exhibition held June 19, 2013 to February 23, 2014.
unknown (Canadian model maker)
core