Results 151 to 160 of about 1,343,028 (316)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

EAEU Role in the Evolution of Multipolar Structure in World Politics

open access: yesЕвразийская интеграция: экономика, право, политика
The global political system is undergoing a transition from a unipolar to a multipolar world. Scientific discussions are underway regarding the emergence or formation of new poles in the world, including the potential development of a pole through the ...
A. V. Toropygin, T. V. Iroshkina
doaj   +1 more source

Process intensification and integration for sustainable design [PDF]

open access: yes, 2021
Foo, Dominic C. Y. 1977-   +2 more
core   +1 more source

Modelling the integration of BP and IT using business process simulation [PDF]

open access: yes, 2005
Information Technology (IT) and Business Process (BP) communities argues that the use of IT to support business processes can bring a number of benefits to the organisation.
den Hengst, M, Serrano, A
core  

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

The integration process

open access: yes
The integration process in Impossible Probability represents the culminating stage in the construction of the Global Artificial Intelligence (GAI), synthesizing two previously established pillars: the Unified Application, emerging from the unification of conceptual categories, and the Artificial Research by Deduction, developed through the ...
openaire   +1 more source

Methodology using process integration for identifying suitable Organic Rankine Cycles for waste heat valorisation [PDF]

open access: yes
The identification of a suitable combined electricity production cycle depends on the heating and cooling requirements of the respective industrial process.
Bendig, Matthias   +2 more
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Factors Influencing Russian Speaking Students' Feeling of Belonging to Promote their Social Integration Process at the University and Society [PDF]

open access: yes
The factors negatively influencing Russian speaking students' feeling of belonging to promote their social integration process at the university and society are as following: 1)the existence of two parallel systems – Latvian and Russian education ...
Roskoša, Antra
core  

A modular tool integration approach : experiences from two case studies [PDF]

open access: yes, 2010
  In the model-driven development process of automotive embedded systems a number of specialized tools are used to support various development tasks. Each tool needs to work seamlessly with artifacts created by other tools to increase the efficiency of ...
Biehl, Matthias,   +2 more
core  

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