Results 101 to 110 of about 25,675,411 (344)

Nanoscale integration of single cell biologics discovery processes using optofluidic manipulation and monitoring. [PDF]

, 2019
The new and rapid advancement in the complexity of biologics drug discovery has been driven by a deeper understanding of biological systems combined with innovative new therapeutic modalities, paving the way to breakthrough therapies for previously ...
Chen, Ching, Chen, Irwin, Chong, Su, Hamburger, Agi, Jess, Philip, Jorgolli, Marsela, Le, Kim, Lin, Fen-Fen, Miranda, Les P, Mock, Marissa, Munro, Trent, Nevill, Tanner, Stevens, Jennitte, Tagari, Philip, Tan, Christopher, Winters, Aaron, Wu, Ming, Xu, Han   +17 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Human Capital as a Driver of Development in the Greater Eurasian Partnership Countries

Евразийская интеграция: экономика, право, политика
The development of human capital in the Eurasian area is the basis for effective cooperation between states. Aim. To define the role of human capital in the framework of the Greater Eurasian Partnership concept and its impact on integration processes in ...
A. A. Krupina
doaj  

The Integration Order of Vector Autoregressive Processes [PDF]

We show that the order of integration of a vector autoregressive process is equal to the difference between the multiplicity of the unit root in the characteristic equation and the multiplicity of the unit root in the adjoint matrix polynomial.
Massimo Franchi
core  

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The Sources and Evolution of Eurasianism

Проблемы постсоветского пространства, 2017
In the recent time we have been witnessing the progressing Eurasian integration processes based on economic integration. In this context, we see the growing interest to Eurasianism that was approached not in terms of the “cold-head calculations”, but as ...
Yulia Evgenievna Shulika
doaj  

Institutional aspects of the political and administrative integration of the Kherson region into the socio-economic space of Russia

RUDN Journal of Public Administration
The study discusses the issues related to the institutional mechanisms of integration of the Kherson region into the political, administrative and socio-economic space of the Russian Federation.
Elena A. Mitrofanova, Michail B. Polyakov, Victor I. Mokrushin   +2 more
doaj   +1 more source

THE IDEAS AND THE PROJECTS OF THE MILITARY AUTHORITIES IN THE CONTEXT OF THE INTEGRATION OF THE NORTH CAUCASUS INTO THE RUSSIAN STATE (THE END OF XVIII - AT THE BEGINNING OF XIX C.)

Гуманитарные и юридические исследования, 2021
The article deals with the projects and ideas about the issue of the North Caucasus integration into the Russian Empire at the end of the XVIII - the beginning of the XIX centuries developed by the region’s military authorities.
T. Kolosovskaya
doaj  

Features of the Strategy of Integration Development of the Eurasian Economic Union

Модернизация, инновация, развитие, 2019
Purpose of the article is to consider the features of the integration development of the Eurasian economic Union and identify possible priority strategic directions.Methods: the presented study is based on a systematic approach. Such universal methods of
T. E. Chekanova
doaj   +1 more source