Results 61 to 70 of about 3,162,958 (354)
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
FEBS Letters, EarlyView.In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
Comparative Institutional and Political Analysis of the European and Eurasian Integration
Управленческое консультирование, 2018 The purpose of this article is to identify common and distinctive characteristics and features of the European and Eurasian integration, the political system and political institutions of the legal entities - European Union (EU) and Eurasian Economic ...
Yana Glittova, Yury Vasilyevich Kosov
doaj
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
FEBS Letters, EarlyView.We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
Human-Centric Process-Aware Information Systems (HC-PAIS) [PDF]
, 2012 Process-Aware Information Systems (PAIS) support organizations in managing and automating their processes. A full automation of processes is in particular industries, such as service-oriented markets, not practicable. The integration of humans in PAIS is
Charoy, Francois +10 more
core +3 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
The Sources and Evolution of Eurasianism
Проблемы постсоветского пространства, 2017 In the recent time we have been witnessing the progressing Eurasian integration processes based on economic integration. In this context, we see the growing interest to Eurasianism that was approached not in terms of the “cold-head calculations”, but as ...
Yulia Evgenievna Shulika
doaj
Balancing Trade‐Offs between Policy Responsiveness and Effectiveness: The Impact of Vertical Policy‐Process Integration on Policy Accumulation [PDF]
, 2020 Christoph Knill +2 more
openalex +1 more source
FEBS Letters, EarlyView.Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
INTEGRATION PROCESSES QUALITY IN HETEROGENOUS ENVIRONMENTS [PDF]
It presents heterogeneous distributed software applications concept. It describes integration techniques. It defines quality of integration processes regarding heterogeneous environments.
Ion Ivan, Leonard Săcuiu
core