Results 81 to 90 of about 3,162,958 (354)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Human Capital as a Driver of Development in the Greater Eurasian Partnership Countries

open access: yesЕвразийская интеграция: экономика, право, политика
The development of human capital in the Eurasian area is the basis for effective cooperation between states. Aim. To define the role of human capital in the framework of the Greater Eurasian Partnership concept and its impact on integration processes in ...
A. A. Krupina
doaj  

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

open access: yesFEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

THE IDEAS AND THE PROJECTS OF THE MILITARY AUTHORITIES IN THE CONTEXT OF THE INTEGRATION OF THE NORTH CAUCASUS INTO THE RUSSIAN STATE (THE END OF XVIII - AT THE BEGINNING OF XIX C.)

open access: yesГуманитарные и юридические исследования, 2021
The article deals with the projects and ideas about the issue of the North Caucasus integration into the Russian Empire at the end of the XVIII - the beginning of the XIX centuries developed by the region’s military authorities.
T. Kolosovskaya
doaj  

Features of the Strategy of Integration Development of the Eurasian Economic Union

open access: yesМодернизация, инновация, развитие, 2019
Purpose of the article is to consider the features of the integration development of the Eurasian economic Union and identify possible priority strategic directions.Methods: the presented study is based on a systematic approach. Such universal methods of
T. E. Chekanova
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Integration processes as catalyst for private equity and venture capital investment [PDF]

open access: yesAnali Ekonomskog fakulteta u Subotici, 2014
The integration process of national economies opens up a great opportunity for foreign capital inflows into the country. One of the challenges in terms of the growing demand for capital, is to take advantage in the best way of this opportunity to attract
Milenković Nada, Andrašić Jelena M.
doaj  

THE CAUCASIAN DIMENSION OF THE EASTERN PARTNERSHIP IN 2009-2016

open access: yesVestnik MGIMO-Universiteta, 2016
The paper gives an in-depth analysis of the evolution of the EU policy towards the South Caucasus within the framework of the Eastern Partnership. It is amply demonstrated that in 2009-2016 the goal was a Europeanization as a creation of a favorable ...
P. A. Barakhvostov
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

MULTILATERAL NEGOTIATIONS, REGIONAL INTEGRATION PROCESSES AND THE CAP. WHAT'S AHEAD? [PDF]

open access: yes
The focus of the paper is on the developments so far and the future of the negotiations on agriculture in the WTO Doha Development Agenda round from the perspective of the European Union.
Anania, Giovanni
core   +1 more source

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