Results 151 to 160 of about 8,449,730 (256)

Facets of integration in the theory and practice of clinical psychology

Current Issues in Personality Psychology, 2017
Lidia Cierpiałkowska
doaj   +1 more source

Apical integration theory provides a neural basis for understanding disorganization and consciousness in the schizophrenias. [PDF]

Curr Res Neurobiol
Silverstein SM, Zolnik T, Larkum M, Thompson JL.   +3 more
europepmc   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Integration effects in border regions - a survey of economic theory and empirical studies [PDF]

Border regions and border effects currently attract a lot of attention in political practice and economic research. Substantial interest in regions located along the frontiers of integrating countries is predominantly inspired by the presumption that ...
Niebuhr, Annekatrin, Stiller, Silvia
core  

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Beyond Stigma-Integrating Neurobiology, Genetics, and Awareness Integration Theory in Addiction Recovery. [PDF]

Psychol Res Behav Manag
Blum K, Gold MS, Jafari N, Lewandrowski KU, Sharafshah A, Mohankumar K, Lorio MP, Bowirrat A, Pinhasov A, Thanos KZ, Elman I, Baron D, Dennen CA, Fuehrlein B, Lewandrowski APL, Modestino EJ, Thanos PK, Zeine F.   +17 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Going green from within: correlational insights into the spread of pro-environmental behavior through the lens of organismic integration theory. [PDF]

Front Psychol
Molkenthin M, Christoforakos L, Hassenzahl M, Laschke M.   +3 more
europepmc   +1 more source

Using Motivated Cue Integration Theory to Understand a Moment-by-Moment Transformative Change: A New Look at the Focusing Technique. [PDF]

Front Hum Neurosci, 2018
Shalev I.
europepmc   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source