Results 121 to 130 of about 652,383 (315)

Microbiome affects mice metabolic homeostasis via differential regulation of gene expression in the brain and gut

Physiological Reports
The gut microbiome (GMB) regulates digestion, metabolism, immunity, and energy homeostasis. This study investigates how gut microbiota integrate the regulation in the neuroendocrine and enteroendocrine systems, with a focus on G protein‐coupled receptors
Wynne Milhouse, Anna Clapp Organski, Xun Sun, Derek Ai, Baohua Zhou, Tzu‐Wen L. Cross, Hongxia Ren   +6 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

CASE STUDIES IN INTEGRATIVE PSYCHOTHERAPY PART 2 (EDITORIAL)

, 2013
Announcement of the special issue of the International Journal of Integrative Psychotherapy, which is dedicated to the exploration and discussion of an integrative psychotherapy case ...
Gregor Žvelc
core  

An Integrative Day Care Clinic for chronically ill patients: Concept and case presentation

, 2012
Introduction: Chronic diseases are one of the biggest challenges for future medicine. Empowering patients to adopt a health promoting lifestyle and to learn effective coping strategies seems essential for successful therapy.
Altner, N, Cramer, H, Langhorst, J, Dobos, GJ, Lauche, R, Paul, A   +5 more
core   +1 more source

Towards Understanding the Relationship Between Personality Types and Homeopathic Remedies in an Integrative Health Approach

Journal of Mind and Medical Sciences
Objective: This study aims to explore the integration of Enneagram personality types with homeopathic prescribing by evaluating the relationship between personality traits and the corresponding homeopathic remedies, enhancing individualized care through ...
Esra Tosun, Ali Timucin Atayoglu
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Integrative Tanztherapie in der Psychiatrischen Tagesklinik

, 2008
Die Abschlussarbeit gibt einen Ausschnitt aus der tanztherapeutischen Arbeit in einer Psychiatrischen Tagesklinik. Das Konzept der Tagesklinik und die theoretischen Grundlagen zur Integrativen Tanztherapie werden beschrieben.
Heinzelmann, Irene
core   +1 more source

Editorial: Dynamic of Transmissible Diseases: Integrative and Transdisciplinary Approaches

Frontiers in Public Health, 2022
Roger Frutos, Laurent Gavotte, Jordi Serra-Cobo, Christian A. Devaux, Christian A. Devaux   +4 more
doaj   +1 more source

Integrative Ecological Notes on Halophytes from „Valea Ilenei” (Iasi) Nature Reserve [PDF]

Memoirs of the Scientific Sections of the Romanian Academy, 2014
Halophytes distribution from Valea Ilenei (Iasi) nature reserve is strictly correlated to environmental factors (soil salinity, humidity), reflecting the morphological and anatomical adaptations found in different species.
Marius-Nicusor Grigore, Constantin Toma
doaj  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source