Results 31 to 40 of about 18,617 (285)

Bioethical implications in the environmental licensing of large enterprises in Brazil [PDF]

, 2017
O processo de licenciamento ambiental de refinarias de petróleo no Brasil tem sido criticado pela ausência do cuidado com relação aos efeitos decorrentes do empreendimento sobre a saúde.
Augusto, Lia Giraldo da Silva, Mendes, José Manuel, Santos, Mariana Olivia dos, Schramm, Fermin Roland, Silva, José Marcos da   +4 more
core   +3 more sources

Neurydynamic Features Of Young People With Different Duration Of Vestibular Illusion [PDF]

, 2019
The article deals with neurodynamic features in persons with different duration of vestibular illusion of rotation. The review of the literature concludes that the time of arbitrary reactions is ensured by a high level of integrative activity of nerve ...
Shmatа, R. (Roman), Vadzyuk, S. (Stepan)   +1 more
core   +3 more sources

Psychiatry beyond the brain: externalism, mental health, and autistic spectrum disorder [PDF]

, 2019
Externalist theories hold that a comprehensive understanding of mental disorder cannot be achieved unless we attend to factors that lie outside of the head: neural explanations alone will not fully capture the complex dependencies that exist between an ...
Glackin, Shane, Krueger, Joel, Roberts, Tom   +2 more
core   +1 more source

Local Investigators Significantly Overestimate Overall Response Rates Compared to Blinded Independent Central Reviews in Uncontrolled Oncology Trials: A Comprehensive Review of the Literature

Frontiers in Pharmacology, 2022
Several drugs gained market authorization based on the demonstration of improved progression-free survival (PFS), adopted as a primary endpoint in Phase 3 clinical trials. In addition, an increasing number of drugs have been granted accelerated approval,
Cinzia Dello Russo, Cinzia Dello Russo, Pierluigi Navarra   +2 more
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Beyond the Metal Flesh: Understanding the Intersection between Bio- and AI Ethics for Robotics in Healthcare

Robotics, 2023
As we look towards the future of healthcare, integrating Care Robots (CRs) into health systems is a practical approach to address challenges such as an ageing population and caregiver shortages.
Auxane Boch, Seamus Ryan, Alexander Kriebitz, Lameck Mbangula Amugongo, Christoph Lütge   +4 more
doaj   +1 more source

Spherical Skin Model: Stratified Co‐Culture of Fibroblasts and Keratinocytes on Spherical Beads Toward Compound Screening

Advanced Healthcare Materials, EarlyView.
Models of the human skin must combine the relevant biological contents and suitable biomaterials with the correct spatial organization. Performing compound screening on such in vitro models also requires fast and reproducible production methods of the models.
Elisa Lenzi, Nadia Vertti‐Quintero, Julien Husson, Anne‐Laure Bulteau, Carine Nizard, Karl Pays, Sébastien Sart, Charles N. Baroud   +7 more
wiley   +1 more source

A Microfluidic Digital Shutter of Liquid–Liquid Interface for Fabrication of Multifaceted Hydrogel Microfiber Structure

Advanced Science, EarlyView.
A programmable passive digital shutter based on multiphase liquid–liquid interface dynamics is introduced for precise fabrication of hydrogel microfibers. By modulating the shutter operation, microfibers with tunable geometry—including linear, helical, tadpole‐like, and spherical forms—are produced.
Dongrui Zhang, Jiangyue Liu, Hao Ye, Yu Shen, Haoran Su, Zhuqing Liang, Kexin Li, Xing Zhang, Shiyi Yang, Yunfei Lu, Zhexi Zhang, Sihang Liu, Yi Huang, Xiao Liu, Yubo Fan   +14 more
wiley   +1 more source

Serum proteomics of active tuberculosis patients and contacts reveals unique processes activated during Mycobacterium tuberculosis infection. [PDF]

, 2020
Tuberculosis (TB) is the most lethal infection among infectious diseases. The specific aim of this study was to establish panels of serum protein biomarkers representative of active TB patients and their household contacts who were either infected (LTBI)
Anibarro, L, Carrera, M, Estévez, O, Gallardo, JM, Gomes-Maueia, C, González-Fernández, Á, Mateos, J, Medina, I, Mussá, T, Nguilichane, A, Pallarés, Á, Reljic, R   +11 more
core   +2 more sources

Label‐Free Molecular Characterization of Protein Aggregates in Differentiated Astrocytes

Advanced Science, EarlyView.
Mid‐infrared photothermal microscopy enables label‐free structural, molecular, and functional imaging of protein aggregates in astrocyte cells. The processes of astrocytes differentiated on a nanomaterial interface are characterized by α‐helical signatures combined with enhanced interfacial thermal resistance properties, while the cell soma of non ...
Panagis D. Samolis, Chiara Lazzarini, Rahmetullah Durgun, Barbara Barile, Giorgia Conte, Tamara Posati, Marco Caprini, Grazia Paola Nicchia, Valentina Benfenati, Michelle Y. Sander   +9 more
wiley   +1 more source