Results 201 to 210 of about 237,722 (258)

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

What do future physicians think of traditional, complementary, and integrative medicine (TCIM)? Fifteen years after the inclusion of TCIM in the Swiss constitution. [PDF]

PLoS One
Berlowitz I, Adler H, Gallego Perez D, Templeton AJ, Wolf U.   +4 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Editorial: Current treatment strategies and integrative medicine for management of pain in sickle cell disease. [PDF]

Front Pain Res (Lausanne)
Richardson KA, McLemore GL, Powell-Roach K, Gupta K.   +3 more
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Exploring the intersection of brain-computer interfaces and traditional, complementary, and integrative medicine. [PDF]

Integr Med Res
Ng JY.
europepmc   +1 more source

Characteristics of prostate cancer patients seeking integrative medicine. [PDF]

J Am Geriatr Soc
Silberlust J, Lampson K, Han K, Li SQ, Mao JJ, Liou KT.   +5 more
europepmc   +1 more source

Multicenter prospective cohort study on colorectal adenoma recurrence and malignant transformation risk based on integrative medicine: a study protocol. [PDF]

Front Oncol
Hui YF, Song SC, Zhu WJ, Bu S, Sun J, Ling TS, Cheng HB.   +6 more
europepmc   +1 more source

Multidisciplinary Integrative Medicine Approach for Cancer Patients: A Multicenter Retrospective Study. [PDF]

Nutrients
Berretta M, Quagliariello V, Ottaiano A, Santorsola M, Di Francia R, Carroccio P, Maurea N, Buonomo OC, Facchini G, Di Mauro G, Montopoli M, Toscano E, Gelsomino C, Picone A, Franchina T, Muscolino P, Bignucolo A, Vanni G, Ciappina G, Montella L.   +19 more
europepmc   +1 more source