Results 101 to 110 of about 570,352 (291)

Repurposing FDA‐Approved Drugs to Inhibit Fungal PPTases for Broad‐Spectrum Synergy

Advanced Science, EarlyView.
Fungal secondary metabolites serve as crucial virulence effectors; however, the potential of their biosynthetic pathways as antifungal targets remains inadequately comprehended. Repurposed FDA‐approved drugs inhibit fungal PPTase (essential for secondary metabolism) in vivo.
Zili Song, Can Zhao, Qiaoling Wang, Hongjiao Zhang, Xiao Liu, Linqi Wang, Michael Bromley, Wen‐Bing Yin   +7 more
wiley   +1 more source

CHST1 Drives Immunotherapy Resistance in Triple‐Negative Breast Cancer by Orchestrating an Immunosuppressive Microenvironment via the NKRF–CCL20–Macrophage Axis

Advanced Science, EarlyView.
Proposed model of CHST1‐associated immune remodeling in triple‐negative breast cancer. In CHST1‐low tumors, greater nuclear accumulation of NKRF is associated with repression of an NF‐κB‐related CCL20 transcriptional program and an immune‐inflamed microenvironment.
Shu‐Hao Jiang, Xiao‐Han Ying, Ruo‐Qing Wang, Qun Zhang, Li Chen, Zhi‐Ming Shao, Jun‐Jie Li   +6 more
wiley   +1 more source

Integrative taxonomy for continental-scale terrestrial insect observations.

PLoS ONE, 2012
Although 21(st) century ecology uses unprecedented technology at the largest spatio-temporal scales in history, the data remain reliant on sound taxonomic practices that derive from 18(th) century science.
Cara M Gibson, Rebecca H Kao, Kali K Blevins, Patrick D Travers   +3 more
doaj   +1 more source

Constrained Forest Methane Sink by Thermal Adaptation of Soil Methanotrophs

Advanced Science, EarlyView.
Climate warming can stimulate methanotroph‐mediated CH4 oxidation in forest soils, thereby mitigating the increase in atmospheric CH4 concentrations. By integrating evidence from a macro‐climatic thermal gradient and a 70‐day incubation experiment, this study demonstrates that microbial methanotrophs can adapt to long‐term temperature changes at the ...
Baizhi Jiang, Xi Zhang, Zhenghu Zhou, Nianpeng He, Xuhui Zhou, Hongyang Chen   +5 more
wiley   +1 more source

Delimiting species of Protaphorura (Collembola: Onychiuridae): integrative evidence based on morphology, DNA sequences and geography

Scientific Reports, 2017
Species delimitation remains a significant challenge when the diagnostic morphological characters are limited. Integrative taxonomy was applied to the genus Protaphorura (Collembola: Onychiuridae), which is one of most difficult soil animals to ...
Xin Sun, Feng Zhang, Yinhuan Ding, Thomas W. Davies, Yu Li, Donghui Wu   +5 more
doaj   +1 more source

How is integrative health care being practiced in clinical centers : mapping the field on the different continents

, 2016
Integrative Health Care services integrate conventional and complementary medicine in one shared context with the aim to treat the whole person. Over the last decades, the number of clinical centers providing integrative health care has increased world ...
Witt, Claudia M., Jong, Miek, Balneaves, Lynda, Hunter, Jennifer (R17944)   +3 more
core  

Integrative taxonomy within the Hylomyscus denniae complex (Rodentia: Muridae) and a new species from Kenya

, 2014
Demos, Terrence C., Agwanda, Bernard, Hickerson, Michael J. (2014): Integrative taxonomy within the Hylomyscus denniae complex (Rodentia: Muridae) and a new species from Kenya.
Agwanda, Bernard, Hickerson, Michael J., Demos, Terrence C.   +2 more
core   +1 more source

Enteric ChAT‐Expressing Neurons Mediate the Protective Effect of Lactobacillus plantarum in Inflammatory Bowel Disease

Advanced Science, EarlyView.
In colitis patients and mice, reduced Lactobacillus abundance is observed. Experimental studies show that L. plantarum A736 metabolizes dietary tryptophan into indole‐3‐lactic acid (ILA), while both L. plantarum A736 and ILA impact ChAT‐expressing enteric neurons and acetylcholine levels, thereby regulating intestinal immune responses and alleviating ...
Bing Xia, Yuwei Sun, Jialin Wang, Yike Liu, Lu Wang, Shiqi Jiang, Gaiyan Bai, Ruijing Zhang, Yu Zhang, Rongwei Kou, Danna Wang, Beita Zhao, Junjie Yi, Yu Fu, Xiaoning Liu, Xuebo Liu   +15 more
wiley   +1 more source

Characteristics of microplastics in tributaries of the upper Brahmaputra River along the Himalayan foothills, India

Environmental Research Communications
Microplastic (MP) pollution is a global concern, yet its presence in riverine environments has received limited research attention. This study aimed to evaluate MP levels and identify their potential sources in river surface water and nearby soil samples
Prasun Goswami, Punyasloke Bhadury
doaj   +1 more source

Abstracts of the 1st International Online Conference on Taxonomy

Biology and Life Sciences Forum
The 1st International Online Conference on Taxonomy (IOCTX2025) serves as a critical interdisciplinary nexus for addressing the contemporary “taxonomic impediment” through the lens of integrative systematics and computational innovation.
Mathias Harzhauser
doaj   +1 more source