Results 121 to 130 of about 22,769 (297)

Sulfated Cyclocarya Paliurus Polysaccharide Sorchestrates the Gut Microbiome to Mobilize a Host‐Derived 12‐HEPE Against Ulcerative Colitis

Advanced Science, EarlyView.
A sulfated polysaccharide (SCP) from Cyclocarya paliurus alleviates ulcerative colitis by reshaping the gut microbiome. This remodeled microbiota orchestrates the upregulation of the host‐derived lipid 12‐HEPE, which directly inhibits the TLR4/NF‐κB pathway to suppress inflammation.
Xianxiang Chen, Mingyue Shen, Rui Zhang, Zhibing Huang, Hui Niu, Qiang Yu, Yi Chen, Xiangwen Pan, Liyuan Rong, Huiliang Wen, Jun Yang, Jianhua Xie   +11 more
wiley   +1 more source

Neuromorphic Near‐Sensor and In‐Sensor Computing Enabled by Next‐Generation Material‐Based Sensors

Advanced Science, EarlyView.
This Review presents a structural framework that classifies neuromorphic sensing into near‐sensor and in‐sensor architectures, clarifying physical coupling between sensing and computation. The framework connects neural and synaptic device functions with recent advances in optical, mechanical, and chemical sensing, compares energy consumption and ...
Su Yeon Jung, Gwang Ya Kim, Sejin Kim, Hyunjong Seo, Se Gi Lee, Sang Min Won, Dongjoon Rhee, Joohoon Kang   +7 more
wiley   +1 more source

Integrative taxonomy of birds : Studies into the nature, origin and delimitation of species

, 2013
Species are the basic currency in biodiversity studies but what constitutes a species has long been controversial. A major breakthough was the insight that most systematists agree that species are segments of population lineages, and that multiple lines ...
Sangster, George,, Ericson, Per G. P.,, Päckert, Martin,   +2 more
core  

How Advanced Artificial Intelligence Technologies Shape Drug–Drug and Drug–Target Interaction Modeling

Advanced Science, EarlyView.
This review explores the convergence of artificial intelligence technologies in modeling drug–drug and drug–target interactions. By evaluating advanced feature engineering, architectural innovations, and learning paradigms reveals shared evolutionary trends and critical challenges, such as cold‐start settings and shortcut learning.
Xin Sun, Tong Wang
wiley   +1 more source

Figure 10. Gill I in Integrative taxonomy of Thalerosphyrus Eatonı 1881 (Ephemeropteraı Heptageniidae) in Thailand

, 2019
Figure 10. Gill I. (a) Thalerosphyrus flowersi. (b) Thalerosphyrus sinuosus. (c) Thalerosphyrus vietnamensis. (d) Thalerosphyrus thailandensis sp.
Sutthacharoenthad, Waranid, Sartori, Michel, Boonsoong, Boonsatien   +2 more
core   +1 more source

Targeting KDM3B Elicits Anti‐tumor Immunity by Alleviating SHP1–mediated STING Suppression in Triple–Negative Breast Cancer

Advanced Science, EarlyView.
P3FI–90 treatment targets KDM3B, reshapes the epigenetic landscape, and suppresses SHP1 expression, thereby activating STING–TBK1–IRF3–type I IFN signaling pathway. Consequently, CD8+ T cells are recruited to the tumor site and activated to produce IFN–γ and GZMB, leading to the killing of TNBC cells.
Xiaolong Wang, Wenhao Li, Yifei Wang, Ning Zhang, Bing Chen, Wenjing Zhao, Lijuan Wang, Dan Luo, Qifeng Yang   +8 more
wiley   +1 more source

Phylogenetics, Molecular Species Delimitation and Geometric Morphometrics of All Reddish-Brown Species in the Genus Neotriplax Lewis, 1887 (Coleoptera: Erotylidae: Tritomini)

Insects
To date, five species of reddish-brown Neotriplax have been described, but their highly similar body color and other phenotypic traits make accurate taxonomy challenging.
Jing Liu, Huixin Xu, Ziqing Wang, Panpan Li, Zihan Yan, Ming Bai, Jing Li   +6 more
doaj   +1 more source

SuFEx‐Enabled Reprogramming of Flavonoids for Selective α‐Glucosidase Covalent Inhibition

Advanced Science, EarlyView.
Selective inhibition of intestinal α‐glucosidase remains limited by poor enzyme specificity and off‐target metabolic effects. Here, SuFEx click chemistry is used to reprogram natural flavonoids into covalent inhibitors with enhanced α‐glucosidase selectivity and controlled reactivity. This strategy enables effective regulation of carbohydrate digestion
Fengyu Guo, Liwei Zhang, Minlong Wang, Yanjin Du, Tianyu Zhang, Hao Chen, Jiazeng Sun, Yang Yu, Zude He, Jie An, Xiaoxu Zhang, Weilin Lin, Fazheng Ren, Pengjie Wang, Ping Liu   +14 more
wiley   +1 more source

Almost nothing left to lose: Suitable habitat for glacial relicts strongly declines under future climate and land use scenarios

Global Ecology and Conservation
Species distributions is shifting, along elevational and latitudinal gradients, likely reflecting the influence of climate change. Yet, land use also influences plant species distribution.
Michael Boxriker, Viktoria Ferenc, Pierre Liancourt, Mike Thiv   +3 more
doaj   +1 more source

Taxonomy of Chrysotoxum festivum Linnaeus, 1758 (Diptera: Syrphidae) - an integrative approach

, 2013
Nedeljković, Zorica, Ačanski, Jelena, Vujić, Ante, Obreht, Dragana, Ðan, Mihajla, Ståhls, Gunilla, Radenković, Snežana (2013): Taxonomy of Chrysotoxum festivum Linnaeus, 1758 (Diptera: Syrphidae) - an integrative approach.
Nedeljković, Zorica, Ðan, Mihajla, Ačanski, Jelena, Obreht, Dragana, Radenković, Snežana, Ståhls, Gunilla, Vujić, Ante   +6 more
core   +1 more source