Results 51 to 60 of about 1,456,433 (267)

Nephrogenic Rests/Nephroblastomatosis in Patients With Unilateral Wilms Tumor Are Not Associated With an Increased Risk of Relapse: An Analysis of Patients Treated on the SIOP‐WT‐2001 Protocol in the SIOP‐UK‐CCLG and SIOP‐GPOH Studies (2001–2022)

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Nephrogenic rests (NRs) and nephroblastomatosis (NBM) are precursor lesions for development of Wilms tumor (WT). Their association with the risk of relapse has not been properly assessed, partly due to misunderstanding of their diagnostic criteria and terminology.
Gordan M. Vujanić, Rhoikos Furtwängler, Tanzina Chowdhury, Christian Vokuhl, Jenny Wegert, Norbert Graf   +5 more
wiley   +1 more source

Hyperelliptic Integrals to Elliptic Integrals

Proceedings of the 2023 International Symposium on Symbolic and Algebraic Computation, 2023
Consider a hyperelliptic integral $I=\int P/(Q\sqrt{S}) dx$, $P,Q,S\in\mathbb{K}[x]$, with $[\mathbb{K}:\mathbb{Q}]<\infty$. When $S$ is of degree $\leq 4$, such integral can be calculated in terms of elementary functions and elliptic integrals of three kinds $\mathcal{F},\mathcal{E},Π$.
openaire   +3 more sources

Occurrence of Extramedullary Relapses in Pediatric Acute Lymphoblastic Leukemia After Treatment With Blinatumomab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We report a retrospective single‐center analysis of pediatric patients with relapsed or refractory B‐cell precursor acute lymphoblastic leukemia focusing on relapses outside of the typical locations, bone marrow, central nervous system, or testes.
Johanna Kunz, Martin Ebinger, Michaela Döring, Markus Mezger, Ursula Holzer, Rupert Handgretinger, Peter Lang, Manon Queudeville   +7 more
wiley   +1 more source

Targeting IP6 signaling to destabilize homologous recombination proteins to overcome PARP inhibitor resistance

Nature Communications
Homologous recombination (HR) is crucial for maintaining genomic integrity and is tightly regulated, yet the role of ubiquitin-dependent degradation in HR proteins remains poorly understood.
Seon-gyeong Lee, Yuri Seo, Seula Jeong, Yuheon Chung, Sukyeong Kong, Minyoung Kim, Joon Ho Rhlee, Sihyeon Um, Bijoy P. Mathew, Saikat Maiti, Malleswara Rao Kuram, Mohamed Ahmed Abozeid, Areum Park, Ji-Na Yoo, Keon Woo Khim, Kyuwon Son, Enkhzul Amarsanaa, Kyunghan Kim, Sehoon Hong, Jiyeon Choi, In Bae Park, Eun A. Lee, Ji Hwan Jeon, Jun Hong Park, Joo Seok Han, Chan Young Park, Seyun Kim, Jang Hyun Choi, Sung You Hong, Min-Duk Seo, Hyuk Lee, Joo-Yong Lee, Kyungjae Myung   +32 more
doaj   +1 more source

Change in Mental Health and Resilience in Childhood Cancer Survivors After Attending a Person‐Centred State‐of‐the‐Art Late Effects Clinic—on Behalf of the PanCareFollowUp Consortium

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Person‐centred follow‐up care based on evidence‐based clinical practice guidelines and providing individualised information should help to inform and reassure survivors about their medical and psychosocial situation and provide treatment and support where needed.
Gisela Michel, Mieke Rijken, Marietta Kokla, Charlotte Sleurs, Jurgen Lemiere, Line Elmerdahl Frederiksen, Luzius Mader, Cecilia Follin, Sara Oberti, Jeanette Falck Winther, Selina R. van den Oever, Leontien C. M. Kremer, Helena J. H. van der Pal, Peter Spreeuwenberg, Eline Bouwman, Jeroen te Dorsthorst, Samira Essiaf, Elizabeth A. M. (Lieke) Feijen, Hannah Gsell, Riccardo Haupt, Maria van Helvoirt, Rosella P. M. G. Hermens, Lars Hjorth, Tomas Kepak, Katerina Kepakova, Anita Kienesberger, Monica Muraca, Marleen Renard, Carina Schneider, Roderick Skinner, Anne Uyttebroeck, Deveny Vanrusselt, Sabine Verschueren, Jacqueline Loonen, Saskia M. F. Pluijm, Katharina Roser, the PanCareFollowUp consortium   +36 more
wiley   +1 more source

Lamin A/C facilitates DNA damage response by modulating ATM signaling and homologous recombination pathways

Animal Cells and Systems
Lamin A/C, a core component of the nuclear lamina, forms a mesh-like structure beneath the inner nuclear membrane. While its structural role is well-studied, its involvement in DNA metabolism remains unclear. We conducted sequential protein fractionation
Seong-jung Kim, Su Hyung Park, Kyungjae Myung, Kyoo-young Lee   +3 more
doaj   +1 more source

Fault Identification in Pipeline System Using Normalized Hilbert Huang Transform and Automatic Selection of Intrinsic Mode Function

MATEC Web of Conferences, 2018
Pressure transient analysis has been widely used to monitor the condition of pipelines and its assessment in water distribution systems. This is a low-cost nonintrusive technique with the ability to locate uncertainties (leak, pipe fitting, blockage) at ...
Yusop Hanafi M., Ghazali M.F., Yusof M.F.M., Remli M.A.Pi, Samykano M.   +4 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Assessing the Performance of a Noninvasive Glucose Monitor in People with Type 2 Diabetes with Different Demographic Profiles

Journal of Diabetes Research, 2017
Background. Noninvasive glucose-monitoring devices represent an exciting frontier in diabetes research. GlucoTrack® is a noninvasive device that indirectly measures glucose fluctuation in the earlobe tissue.
Karnit Bahartan, Keren Horman, Avner Gal, Andrew Drexler, Yulia Mayzel, Tamar Lin   +5 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source