Results 31 to 40 of about 134,040 (218)

Allocation Fragments of the Distributed Database

open access: yesCommunications, 2003
The paper describes the distribution fragments of the database under a mathematical model with criterial function involving the influence of the Transaction and Concurrency proccesing in Database systems. The model could solve variants for replication of
Karol Matiasko
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Deriving Triggers from Integrity Constraint Specifications in the Database Management Systems

open access: yesActa Polytechnica, 2001
Supporting integrity constraints is essential for database systems. Integrity constraints are used to ensure that the data in a database complies with rules that have been set to establish accurate and acceptable information for a database.
M. Badawy, K. Richta
doaj  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

STUDY ON THE MATCHING OF CRACK-TIP CONSTRAINTS AMONG DIFFERENT LABORATORY SPECIMENS

open access: yesJixie qiangdu, 2019
The matching of crack tip constraints is a difficult problem in the current structure integrity assessment method.Due to the restriction of current constraint parameters,the matching of crack tip constraints between different laboratory specimens,between
YANG Jie, LIU YuMan, WU Fan
doaj  

Route-Integrity Constraints for Inland-Vessel Speed Planning: Detecting and Limiting Segment-Level Burden Transfer

open access: yesJournal of Marine Science and Engineering
Inland-vessel speed reductions targeted at priority segments can reallocate a normalized burden proxy across a fixed corridor. We develop a route-integrity speed-planning model that accepts a plan only when it attains the priority target, preserves route-
Chenyu Wang, Jiaqi Xu, Xiangwei Liu
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

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