Results 41 to 50 of about 134,040 (218)
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Communications Earth & EnvironmentDepleted oil and gas reservoirs provide an opportunity to repurpose underperforming wells and reuse existing subsurface infrastructure to support Net Zero transitions.
Nikhil S. Rajput +3 more
doaj +1 more source
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Molecular Oncology, EarlyView.Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
Survey on Secure Scientific Workflow Scheduling in Cloud Environments
Future InternetIn cloud computing environments, the representation and management of data through workflows are crucial to ensuring efficient processing. This paper focuses on securing scientific workflow scheduling, which involves executing complex data-processing ...
Hadeel Amjed Saeed +3 more
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Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
A Methodology for Vertically Partitioning in a Multi-Relation Database Environment
Journal of Computer Science and Technology, 2007 Vertical partitioning, in which attributes of a relation are assigned to partitions, is aimed at improving database performance. We extend previous research that is based on a single relation to multi-relation database environment, by including ...
Narasimhaiah Gorla
doaj
Residual stress analysis of thin AlSi10Mg parts produced by Laser Powder Bed Fusion
Virtual and Physical Prototyping, 2020 Among the various Additive Manufacturing (AM) technologies available for metal part production, powder bed processes are the most promising for industrial mass production.
Alessandro Salmi, Eleonora Atzeni
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Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source