Results 61 to 70 of about 336,071 (307)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Design and implementation of a model for OS kernel integrity protection
Tongxin xuebao, 2015 Untrusted kernel extensions were considered to be a big threat to OS kernel integrity because once they were loaded into the kernel space,then they may corrupt both the OS kernel data and code at will.To address this problem,MAC-based model named MOKIP ...
Dong-hai TIAN +3 more
doaj
System Integrity Protection Schemes: Naming Conventions and the Need for Standardization
Energies, 2022 The energy transition is placing increased strain on power systems and making it challenging for Transmission System Operators (TSOs) to securely operate power systems. System Integrity Protection Schemes (SIPSs) are one of the solutions to address these
Stefan Stanković +2 more
doaj +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Integrity of Medicare customer data [PDF]
, 2014 This audit examined the effectiveness of the Department of Human Services’ management of Medicare customer data and the integrity of this data. Audit objective, criteria and scope The objective of the audit was to examine the effectiveness of the ...
core
Environmental Integrity Index Phase 1 (2003) Watersheds Report
, 2006 This report contains a massive amount of data regarding the contributing factors to the EII score. There are graphs showing how Waller Creek compares to nearby watersheds with a variety of water quality metrics, as well as a diatom list of organisms ...
Clamann, Andrew, Harrison, Jeremy
core +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Online Personal Data Processing and EU Data Protection Reform. CEPS Task Force Report, April 2013 [PDF]
, 2013 This report sheds light on the fundamental questions and underlying tensions between current policy objectives, compliance strategies and global trends in online personal data processing, assessing the existing and future framework in terms of effective ...
Luchetta, Giacomo, Irion, Kristina
core
INDUSTRIAL PACKAGING: TECHNOLOGY, APPLICATIONS AND PRECAUTIONS IN THE CASE OF PALLETIZED PRODUCTS [PDF]
Proceedings on Engineering Sciences, 2019 The packaging sector is rapidly rising in the last years and it is continuously looking for new techniques for development and optimization. In this industrial sector the producer has the target to ensure a packaging able to contain the load within a ...
Alessandro Greco +3 more
doaj +1 more source